CAS 116285-77-9|8-Chloroinosine

Introduction:Basic information about CAS 116285-77-9|8-Chloroinosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name8-Chloroinosine
CAS Number116285-77-9Molecular Weight302.67
Density2.19 g/cm3Boiling Point722.7ºC at 760 mmHg
Molecular FormulaC10H11ClN4O5Melting Point/
MSDS/Flash Point390.8ºC

Names

Name8-Chloroinosine
SynonymMore Synonyms

8-Chloroinosine BiologicalActivity

Description8-Chloroinosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Density2.19 g/cm3
Boiling Point722.7ºC at 760 mmHg
Molecular FormulaC10H11ClN4O5
Molecular Weight302.67
Flash Point390.8ºC
Exact Mass302.04200
PSA133.49000
Vapour Pressure0mmHg at 25°C
Index of Refraction1.886
InChIKeyROPMUQKCJYNROP-UUOKFMHZSA-N
SMILESO=c1[nH]cnc2c1nc(Cl)n2C1OC(CO)C(O)C1O

Synonyms

8-chloroinosine
CAS 85562-55-6|Adenosine,8-chloro-2'-deoxy- (9CI)
CAS 14365-44-7|Adenosine,5'-amino-5'-deoxy-
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