Introduction：Basic information about CAS 14365-44-7|Adenosine,5'-amino-5'-deoxy-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Adenosine,5'-amino-5'-deoxy- |
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| CAS Number | 14365-44-7 | Molecular Weight | 266.26 |
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| Density | 2.08 g/cm3 | Boiling Point | 647.6ºC at 760 mmHg |
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| Molecular Formula | C10H14N6O3 | Melting Point | / |
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| MSDS | / | Flash Point | 345.4ºC |
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Names
| Name | 5'-aminoadenosine |
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| Synonym | More Synonyms |
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Adenosine,5'-amino-5'-deoxy- BiologicalActivity
| Description | 5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 2.08 g/cm3 |
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| Boiling Point | 647.6ºC at 760 mmHg |
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| Molecular Formula | C10H14N6O3 |
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| Molecular Weight | 266.26 |
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| Flash Point | 345.4ºC |
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| Exact Mass | 266.11300 |
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| PSA | 145.33000 |
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| Vapour Pressure | 1.18E-17mmHg at 25°C |
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| Index of Refraction | 1.935 |
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| InChIKey | GVSGUDGNTHCZHI-KQYNXXCUSA-N |
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| SMILES | NCC1OC(n2cnc3c(N)ncnc32)C(O)C1O |
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Synonyms
| 5'-amino-5'-deoxyAdo |
| 5-amino-5-deoxyadenosine |
| 5'-AMINO-5'-DEOXY-D-ADENOSINE |
| 5'-Deoxy-5'-aminoadenosine |
| 5'-amino-2',3'-O-isopropylidene-5'-deoxyadenosine |
| 5'-NH-ADO |
| Adenosine,5'-aMino-5'-deoxy |
