CAS 50632-57-0|2-Methoxy-2,4-diphenyl-3(2H)-furanone
| Common Name | 2-Methoxy-2,4-diphenyl-3(2H)-furanone | ||
|---|---|---|---|
| CAS Number | 50632-57-0 | Molecular Weight | 266.291 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 426.6±45.0 °C at 760 mmHg |
| Molecular Formula | C17H14O3 | Melting Point | 96ºC |
| MSDS | ChineseUSA | Flash Point | 203.6±15.1 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 2-methoxy-2,4-diphenylfuran-3-one |
|---|---|
| Synonym | More Synonyms |
2-Methoxy-2,4-diphenyl-3(2H)-furanone BiologicalActivity
| Description | 2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>MMP |
| References | [1]. Peter Jackson. Detection of phosphoproteins. WO2006070180. [2]. Danqing Min, et al. 2-Methoxy-2,4-diphenyl-3(2H)-furanone-labeled gelatin zymography and reverse zymography: a rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases. Electrophoresis. 20 |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 426.6±45.0 °C at 760 mmHg |
| Melting Point | 96ºC |
| Molecular Formula | C17H14O3 |
| Molecular Weight | 266.291 |
| Flash Point | 203.6±15.1 °C |
| Exact Mass | 266.094299 |
| PSA | 35.53000 |
| LogP | 3.48 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.618 |
| InChIKey | BLWINLJDTOJSRU-UHFFFAOYSA-N |
| SMILES | COC1(c2ccccc2)OC=C(c2ccccc2)C1=O |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2932190090 |
Customs
| HS Code | 2932190090 |
|---|---|
| Summary | 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
Articles22
More Articles| Proteolytic activity and cytokine up-regulation by non-albicans Candida albicans. Arch. Microbiol. 197(4) , 533-7, (2015) Mouth is an important source of infections and oral infections such as Candida infections increase the risk of mortality. Our purpose was to investigate differences in proteolytic activity of non-albi... | |
| Fluorescent labeling of proteins with nile red and 2-methoxy-2,4-diphenyl-3(2H)-furanone: physicochemical basis and application to the rapid staining of sodium dodecyl sulfate polyacrylamide gels and Western blots. Electrophoresis 22(5) , 874-80, (2001) The fluorescent hydrophobic dye Nile red allows the rapid, sensitive, and general staining of proteins in sodium dodecyl sulfate (SDS)-polyacrylamide gels. Nile red staining does not preclude further ... | |
| Rapid imaging, using a cooled charge-coupled-device, of fluorescent two-dimensional polyacrylamide gels produced by labelling proteins in the first-dimensional isoelectric focusing gel with the fluorophore 2-methoxy-2,4-diphenyl-3(2H)furanone. Electrophoresis 9(7) , 330-9, (1988) A new method for visualising proteins in two-dimensional polyacrylamide gels was developed. Proteins were labelled with the fluorophore 2-methoxy-2,4-diphenyl-3(2H)furanone (MDPF) while present in the... |
Synonyms
| 2-Methoxy-2,4-diphenylfuran-3(2H)-one |
| MFCD00036834 |
| 3(2H)-Furanone, 2-methoxy-2,4-diphenyl- |
| 2-Mdpf |
| 2-Methoxy-2,4-diphenyl-3(2H)-furanone |
| MDPF |
| 2,4-Diphenyl-2-methoxy-3(2H)-furanone,MDPF |
| 2-methoxy-2,4-diphenyl-furan-3-one |
