CAS 69304-49-0|(E)-4,4,4-TRIFLUORO-1-PHENYL-BUT-2-EN-1-ONE
Introduction：Basic information about CAS 69304-49-0|(E)-4,4,4-TRIFLUORO-1-PHENYL-BUT-2-EN-1-ONE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (E)-4,4,4-TRIFLUORO-1-PHENYL-BUT-2-EN-1-ONE | ||
|---|---|---|---|
| CAS Number | 69304-49-0 | Molecular Weight | 217.02000 |
| Density | 1.881g/cm3 | Boiling Point | / |
| Molecular Formula | C6H5BrN2O2 | Melting Point | 189-194ºC (dec.)(lit.) |
| MSDS | USA | Flash Point | / |
Names
| Name | 5-[(E)-2-bromoethenyl]-1H-pyrimidine-2,4-dione |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.881g/cm3 |
|---|---|
| Melting Point | 189-194ºC (dec.)(lit.) |
| Molecular Formula | C6H5BrN2O2 |
| Molecular Weight | 217.02000 |
| Exact Mass | 215.95300 |
| PSA | 65.72000 |
| LogP | 0.42880 |
| Index of Refraction | 1.685 |
| InChIKey | BLXGZIDBSXVMLU-OWOJBTEDSA-N |
| SMILES | O=c1[nH]cc(C=CBr)c(=O)[nH]1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 200 mg/L
- REFERENCE :
- LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 38,281,1986
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 200 mg/L
- REFERENCE :
- LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 38,281,1986
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| RTECS | UV9020500 |
Articles21
More Articles| Biochemical modulation of the catabolism and tissue uptake of the anticancer drug 5-fluorouracil by 5-bromovinyluracil: assessment with metabolic (19)F MR imaging. Magn. Reson. Med. 42(5) , 936-43, (1999) Using chemical shift-selective (19)F magnetic resonance (MR) imaging, we investigated the biomodulating action of 5-bromovinyluracil (BVU) on the degradation of the anticancer drug 5-fluorouracil (5-F... | |
| Deoxyribosyl exchange reactions leading to the in vivo generation and regeneration of the antiviral agents (E)-5-(2-bromovinyl)-2'-deoxyuridine, 5-ethyl-2'-deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine. Biochem. Pharmacol. 35(10) , 1647-53, (1986) In the rat, the highly potent anti-herpes drug (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVdUrd) is rapidly converted to its base (E)-5-(2-bromovinyl)uracil (BVUra) through the action of pyrimidine nucleo... | |
| Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridine. J. Med. Chem. 29 , 213, (1986) (E)-5-(2-Bromovinyl)uracil (BVU) and (E)-5-(2-bromovinyl)uridine (BVRU) were synthesized starting from 5-formyluracil via (E)-5-(2-carboxyvinyl)uracil or starting from 5-iodouridine via (E)-5-(2-carbo... |
Synonyms
| BV uracil |
| 5-bromovinyluracil |
| Bromovinyluracil |
| MFCD00132885 |
