CAS 603-45-2|Aurin

Introduction:Basic information about CAS 603-45-2|Aurin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAurin
CAS Number603-45-2Molecular Weight290.31
Density1.3±0.1 g/cm3Boiling Point543.0±50.0 °C at 760 mmHg
Molecular FormulaC19H14O3Melting Pointca. 308ºC (decomposes)
MSDSUSAFlash Point296.2±26.6 °C

Names

Name4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one
SynonymMore Synonyms

Aurin BiologicalActivity

DescriptionRosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1].
Related CatalogSignaling Pathways >>NF-κB >>Keap1-Nrf2Research Areas >>Metabolic Disease
References

[1]. Amin KN, et al. Effect of Rosolic acid on endothelial dysfunction under ER stress in pancreatic microenvironment. Free Radic Res. 2021 Jun;55(6):698-713.  

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point543.0±50.0 °C at 760 mmHg
Melting Pointca. 308ºC (decomposes)
Molecular FormulaC19H14O3
Molecular Weight290.31
Flash Point296.2±26.6 °C
Exact Mass290.094299
PSA57.53000
LogP3.15
Vapour Pressure0.0±1.5 mmHg at 25°C
Index of Refraction1.691
InChIKeyFYEHYMARPSSOBO-UHFFFAOYSA-N
SMILESO=C1C=CC(=C(c2ccc(O)cc2)c2ccc(O)cc2)C=C1
Storage conditionStore at room temperature.
Water SolubilitySolubility Practically insoluble in water, benzene; freely soluble in ethanol

Safety Information

Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2914501900

Customs

HS Code2914501900
Summary2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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Synonyms

4-(p,p'-Dihydroxybenzhydrylidene)-2,5-cyclohexadien-1-one
Aurin No. 555
MFCD00001624
2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]-
EINECS 210-041-8
4-[bis(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one
Aurin
4-<bis(4-hydroxyphenyl)methylene>-2,5-cyclohexadienone
2,5-Cyclohexadien-1-one, 4-(bis(4-hydroxyphenyl)methylene)-
rosolic acid
4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one
Corallin Spirit Soluble
4,4'-Dihydroxyfuchsone
4-(Bis(p-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one
4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one
Aurine
Corallin
p-Rosolic acid
Spirit Aurine
4-[bis-(4-hydroxyphenyl)methylene]-cyclohexa-2,5-dienone
Rosalic Acid
CI 43800
Pararosolic Acid
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