Introduction：Basic information about CAS 37065-29-5|miloxacin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | miloxacin |
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| CAS Number | 37065-29-5 | Molecular Weight | 263.203 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 460.9±55.0 °C at 760 mmHg |
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| Molecular Formula | C12H9NO6 | Melting Point | 264° (dec) |
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| MSDS | / | Flash Point | 232.5±31.5 °C |
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Names
| Name | 5-methoxy-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 460.9±55.0 °C at 760 mmHg |
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| Melting Point | 264° (dec) |
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| Molecular Formula | C12H9NO6 |
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| Molecular Weight | 263.203 |
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| Flash Point | 232.5±31.5 °C |
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| Exact Mass | 263.042999 |
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| PSA | 86.99000 |
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| LogP | 1.34 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.689 |
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| InChIKey | ABQYZRZVRIPTPI-UHFFFAOYSA-N |
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| SMILES | COn1cc(C(=O)O)c(=O)c2cc3c(cc21)OCO3 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- JI5060000
- CHEMICAL NAME :
- 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-5-methoxy-8-oxo-
- CAS REGISTRY NUMBER :
- 37065-29-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H9-N-O6
- MOLECULAR WEIGHT :
- 263.22
- WISWESSER LINE NOTATION :
- T C566 DO FO JN MV EHJ JO1 LVQ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 36400 mg/kg/26W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in uterine weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 413 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1650 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - parturition
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3300 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8100 mg/kg
- SEX/DURATION :
- female 17-22 day(s) after conception lactating female 21 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - physical
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 140 ug/L
- REFERENCE :
- AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 17,763,1980
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1,3-Dioxolo[4,5-g]quinoline-7-carboxylic acid, 5,8-dihydro-5-methoxy-8-oxo- |
| miloxacin |
| Antibiotic AB 206 |
| 5-Methoxy-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid |
| AB 206 |
