CAS 93285-75-7|Iodoacetyl-LC-biotin

Introduction：Basic information about CAS 93285-75-7|Iodoacetyl-LC-biotin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Iodoacetyl-LC-biotin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Iodoacetyl-LC-biotin
CAS Number	93285-75-7	Molecular Weight	510.43300
Density	1.414g/cm3	Boiling Point	793.7ºC at 760 mmHg
Molecular Formula	C₁₈H₃₁IN₄O₃S	Melting Point	/
MSDS	/	Flash Point	433.8ºC

Names

Name	n-iodoacetyl-n-biotinylhexylenediamine
Synonym	More Synonyms

Iodoacetyl-LC-biotin BiologicalActivity

Description	Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Others
In Vitro	Iodoacetyl-LC-biotin (IAB) (50-200 μM; 6-24 h) increases LDH leakage in HEK293 cells in a time- and dose-dependant manner[1]. IAB (50-200 µM; 24 h) causes the release of cytochrome c from the mitochondria to the cytosol in HEK293 cells[1].
References	[1]. Wong HL, et, al. Mitochondrial protein targets of thiol-reactive electrophiles. Chem Res Toxicol. 2008 Apr;21(4):796-804. [2]. Davis KA, et, al. Staining of cell surface human CD4 with 2'-F-pyrimidine-containing RNA aptamers for flow cytometry. Nucleic Acids Res. 1998 Sep 1;26(17):3915-24.

Chemical & Physical Properties

Density	1.414g/cm3
Boiling Point	793.7ºC at 760 mmHg
Molecular Formula	C₁₈H₃₁IN₄O₃S
Molecular Weight	510.43300
Flash Point	433.8ºC
Exact Mass	510.11600
PSA	124.63000
LogP	3.37940
Index of Refraction	1.559
InChIKey	DNXDWMHPTVQBIP-ZQIUZPCESA-N
SMILES	O=C(CI)NCCCCCCNC(=O)CCCCC1SCC2NC(=O)NC21

Safety Information

Hazard Codes	Xi

Synonyms

N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine

N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE

iodoacetyl-LC-biotin

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