CAS 60-25-3|a,w-bis(trimethylammonium)hexane dichloride
Introduction：Basic information about CAS 60-25-3|a,w-bis(trimethylammonium)hexane dichloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Hexamethonium Chloride Dihydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
Research Areas >>Others
Chemical & Physical Properties
Melting Point
292 °C(dec.)
Molecular Formula
C12H30Cl2N2
Molecular Weight
273.286
Exact Mass
272.178589
InChIKey
PYIHTIJNCRKDBV-UHFFFAOYSA-L
SMILES
C[N+](C)(C)CCCCCC[N+](C)(C)C.[Cl-].[Cl-]
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
BQ8650000
CHEMICAL NAME :
Ammonium, hexamethylenebis(trimethyl-, dichloride
CAS REGISTRY NUMBER :
60-25-3
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C12-H30-N2.2Cl
MOLECULAR WEIGHT :
273.34
WISWESSER LINE NOTATION :
1K1&1&6K1&1&1 &Q 2 &G 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,346,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
62 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 155,69,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
26700 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 127,1,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
35 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,346,1957
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
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