CAS 90-80-2|Delta-Gluconolactone

Introduction:Basic information about CAS 90-80-2|Delta-Gluconolactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDelta-Gluconolactone
CAS Number90-80-2Molecular Weight178.140
Density0.6Boiling Point230.35°C
Molecular FormulaC6H10O6Melting Point151-155 ºC
MSDSChineseUSAFlash Point192.3±20.3 °C

Names

NameD-glucono-1,5-lactone
SynonymMore Synonyms

Delta-Gluconolactone BiologicalActivity

DescriptionD-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.
Related CatalogNatural Products >>Saccharides and GlycosidesResearch Areas >>Others
Target

Human Endogenous Metabolite

In VitroD-(+)-Glucono-1,5-lactone is a lactone (cyclic ester) of D-gluconic acid. D-(+)-Glucono-1,5-lactone is commonly found in honey, fruit juices, personal lubricants, and wine. D-(+)-Glucono-1,5-lactone is neutral, but hydrolyses in water to gluconic acid which is acidic, adding a tangy taste to foods, though it has roughly a third of the sourness of citric acid. It is metabolized to glucose; one gram of D-(+)-Glucono-1,5-lactone yields roughly the same amount of metabolicenergy as one gram of sugar. Upon addition to water, GDL is partially hydrolysed to gluconic acid, with the balance between the lactone form and the acid form established as a chemical equilibrium. The rate of hydrolysis of D-(+)-Glucono-1,5-lactone is increased by heat and high pH[1].
References

[1]. Xu Y, et al. Aggregation and structural changes of silver carp actomyosin as affected by mild acidification with D-gluconic acid δ-lactone. Food Chem. 2012 Sep 15;134(2):1005-10.

Chemical & Physical Properties

Density0.6
Boiling Point230.35°C
Melting Point151-155 ºC
Molecular FormulaC6H10O6
Molecular Weight178.140
Flash Point192.3±20.3 °C
Exact Mass178.047745
PSA107.22000
LogP-2.38
Vapour Pressure0.0±2.4 mmHg at 25°C
Index of Refraction1.608
InChIKeyPHOQVHQSTUBQQK-SQOUGZDYSA-N
SMILESO=C1OC(CO)C(O)C(O)C1O
Water Solubility500 g/L (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ5184000
CHEMICAL NAME :
Gluconic acid, delta-lactone, D-
CAS REGISTRY NUMBER :
90-80-2
LAST UPDATED :
199803
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H10-O6
MOLECULAR WEIGHT :
178.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
5 mmol/L
REFERENCE :
AMICCW Archives of Microbiology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secacus, NJ 07094) V.95- 1974- Volume(issue)/page/year: 109,157,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80419 No. of Facilities: 3748 (estimated) No. of Industries: 25 No. of Occupations: 33 No. of Employees: 20328 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80419 No. of Facilities: 3645 (estimated) No. of Industries: 12 No. of Occupations: 28 No. of Employees: 184229 (estimated) No. of Female Employees: 157249 (estimated)

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXn: Harmful;Xi: Irritant;
Risk PhrasesR21
Safety PhrasesS24/25
RIDADRNONH for all modes of transport
WGK Germany3
RTECSLZ5184000
HS Code2932999099

Customs

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles44

More Articles
The EpiOcular Eye Irritation Test (EIT) for hazard identification and labelling of eye irritating chemicals: protocol optimisation for solid materials and the results after extended shipment.

Altern. Lab. Anim. 43 , 101-27, (2015)

The 7th Amendment to the EU Cosmetics Directive and the EU REACH Regulation have reinforced the need for in vitro ocular test methods. Validated in vitro ocular toxicity tests that can predict the hum...

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Dehydrodipeptide Hydrogelators Containing Naproxen N-Capped Tryptophan: Self-Assembly, Hydrogel Characterization, and Evaluation as Potential Drug Nanocarriers.

Biomacromolecules 16 , 3562-73, (2015)

In this work, we introduce dipeptides containing tryptophan N-capped with the nonsteroidal anti-inflammatory drug naproxen and C-terminal dehydroamino acids, dehydrophenylalanine (ΔPhe), dehydroaminob...

Synonyms

D-Gluconolactone
EINECS 202-016-5
δ-Gluconolactone
(3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one
D-Gluconic acid-1,5-lactone
D-Glucono-1,5-lactone
D-Glucono-d-lactone
gluconolactone
D-Gluconic acid 1,5-lactone
d-gluconic acid d-lactone
Delta-Gluconolactone
Gluconic acid lactone
δ-Gluconic acid d-lactone
δ-Gluconic acid δ-lactone
MFCD00006647
Glucono δ-lactone
D-Gluconic acid lactone
D-Gluconic acid, δ-lactone
D-(+)-Glucono-1,5-lactone
CAS 3847-29-8|n-2,10-dion(1:1)
CAS 7681-11-0|Potassium iodide
Recommended......
TOP