Introduction:Basic information about CAS 90-80-2|Delta-Gluconolactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.
Related Catalog
Natural Products >>Saccharides and GlycosidesResearch Areas >>Others
Target
Human Endogenous Metabolite
In Vitro
D-(+)-Glucono-1,5-lactone is a lactone (cyclic ester) of D-gluconic acid. D-(+)-Glucono-1,5-lactone is commonly found in honey, fruit juices, personal lubricants, and wine. D-(+)-Glucono-1,5-lactone is neutral, but hydrolyses in water to gluconic acid which is acidic, adding a tangy taste to foods, though it has roughly a third of the sourness of citric acid. It is metabolized to glucose; one gram of D-(+)-Glucono-1,5-lactone yields roughly the same amount of metabolicenergy as one gram of sugar. Upon addition to water, GDL is partially hydrolysed to gluconic acid, with the balance between the lactone form and the acid form established as a chemical equilibrium. The rate of hydrolysis of D-(+)-Glucono-1,5-lactone is increased by heat and high pH[1].
References
[1]. Xu Y, et al. Aggregation and structural changes of silver carp actomyosin as affected by mild acidification with D-gluconic acid δ-lactone. Food Chem. 2012 Sep 15;134(2):1005-10.
Chemical & Physical Properties
Density
0.6
Boiling Point
230.35°C
Melting Point
151-155 ºC
Molecular Formula
C6H10O6
Molecular Weight
178.140
Flash Point
192.3±20.3 °C
Exact Mass
178.047745
PSA
107.22000
LogP
-2.38
Vapour Pressure
0.0±2.4 mmHg at 25°C
Index of Refraction
1.608
InChIKey
PHOQVHQSTUBQQK-SQOUGZDYSA-N
SMILES
O=C1OC(CO)C(O)C(O)C1O
Water Solubility
500 g/L (20 ºC)
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
LZ5184000
CHEMICAL NAME :
Gluconic acid, delta-lactone, D-
CAS REGISTRY NUMBER :
90-80-2
LAST UPDATED :
199803
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H10-O6
MOLECULAR WEIGHT :
178.16
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
5 mmol/L
REFERENCE :
AMICCW Archives of Microbiology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secacus, NJ 07094) V.95- 1974- Volume(issue)/page/year: 109,157,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80419 No. of Facilities: 3748 (estimated) No. of Industries: 25 No. of Occupations: 33 No. of Employees: 20328 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80419 No. of Facilities: 3645 (estimated) No. of Industries: 12 No. of Occupations: 28 No. of Employees: 184229 (estimated) No. of Female Employees: 157249 (estimated)
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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