CAS 93-15-2|Methyleugenol
Introduction：Basic information about CAS 93-15-2|Methyleugenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyleugenol | ||
|---|---|---|---|
| CAS Number | 93-15-2 | Molecular Weight | 178.228 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 254.7±0.0 °C at 760 mmHg |
| Molecular Formula | C11H14O2 | Melting Point | −4 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 87.1±22.7 °C |
| Symbol | GHS07, GHS08, GHS09 | Signal Word | Warning |
Names
| Name | O-methyleugenol |
|---|---|
| Synonym | More Synonyms |
Methyleugenol BiologicalActivity
| Description | Methyl Eugenol, a phenylpropanoid chemical in leaves, fruits, stems, and/or roots, may be released when that corresponding part of a plant is damaged as a result of feeding by an herbivore. Methyl Eugenol is used for male annihilation of the oriental fruit fly[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Tan KH, et al. Methyl eugenol: its occurrence, distribution, and role in nature, especially in relation to insect behavior and pollination. J Insect Sci. 2012;12:56. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 254.7±0.0 °C at 760 mmHg |
| Melting Point | −4 °C(lit.) |
| Molecular Formula | C11H14O2 |
| Molecular Weight | 178.228 |
| Flash Point | 87.1±22.7 °C |
| Exact Mass | 178.099380 |
| PSA | 18.46000 |
| LogP | 2.97 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.500 |
| InChIKey | ZYEMGPIYFIJGTP-UHFFFAOYSA-N |
| SMILES | C=CCc1ccc(OC)c(OC)c1 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Water Solubility | insoluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 810 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4800 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 540 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - somnolence (general depressed activity) Behavioral - altered sleep time (including change in righting reflex)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 112 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - somnolence (general depressed activity) Behavioral - altered sleep time (including change in righting reflex)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2025 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4200 mg/kg/6W-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- Unscheduled DNA synthesis
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 5,1613,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 04500 No. of Facilities: 41 (estimated) No. of Industries: 2 No. of Occupations: 21 No. of Employees: 2840 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 04500 No. of Facilities: 1074 (estimated) No. of Industries: 5 No. of Occupations: 10 No. of Employees: 12682 (estimated) No. of Female Employees: 9413 (estimated)
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 5,1613,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 04500 No. of Facilities: 41 (estimated) No. of Industries: 2 No. of Occupations: 21 No. of Employees: 2840 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 04500 No. of Facilities: 1074 (estimated) No. of Industries: 5 No. of Occupations: 10 No. of Employees: 12682 (estimated) No. of Female Employees: 9413 (estimated)
Safety Information
| Symbol | GHS07, GHS08, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335-H351-H411 |
| Precautionary Statements | P280-P301 + P312 + P330-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22;R36/37/38;R40 |
| Safety Phrases | S26-S36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | CY2450000 |
| HS Code | 29093090 |
Customs
| HS Code | 2909309090 |
|---|---|
| Summary | 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
Articles40
More Articles| The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat. Food Chem. Toxicol. 74 , 28-34, (2014) The alkenylbenzene methyleugenol occurs naturally in a variety of spices and herbs, including basil, and their essential oils. At high dose levels methyleugenol induces hepatocarcinogenicity in rodent... | |
| Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations. Toxicol. Appl. Pharmacol. 283(2) , 117-26, (2015) The present study aims at predicting the level of formation of the ultimate carcinogenic metabolite of methyleugenol, 1'-sulfooxymethyleugenol, in the human population by taking variability in key bio... | |
| Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages. Bioorg. Med. Chem. Lett. 15 , 1949-53, (2005) 1'S-1'-Acetoxychavicol acetate from the rhizomes of Alpinia galanga inhibited nitric oxide (NO) production in lipopolysaccharide-activated mouse peritoneal macrophages with an IC(50) value of 2.3 micr... |
Synonyms
| EINECS 202-223-0 |
| FEMA 2475 |
| 1U2R CO1 DO1 |
| methyl eugenol |
| 4-Allylveratrole |
| 1,2-dimethoxy-4-(2-propen-1-yl)benzene |
| 1,3,4-eugenol methyl ether |
| O-Methyl eugenol |
| LEVO-ROSE OXIDE |
| Eugenol methyl ether |
| 4-Allyl-1,2-dimethoxybenzene |
| 3,4-dimethoxyallylbenzene |
| 3-METHYLEUGENOL |
| 1-allyl-3,4-dimethoxybenzene |
| Allyl veratrole |
| femanumber2475 |
| O-Methyleugenol |
| Eugenyl methyl ether |
| 1,2-dimethoxy-4-(prop-2-en-1-yl)benzene |
| Methyleugenol |
| Benzene, 1,2-dimethoxy-4-(2-propen-1-yl)- |
| MFCD00008652 |
| 1-(3,4-Dimethoxyphenyl)-2-propene |
| 4-Allylveratrol |
