CAS 66104-22-1|Pergolide

Introduction：Basic information about CAS 66104-22-1|Pergolide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Pergolide BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Pergolide
CAS Number	66104-22-1	Molecular Weight	314.488
Density	1.1±0.1 g/cm3	Boiling Point	491.3±35.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₆N₂S	Melting Point	207.5ºC
MSDS	/	Flash Point	250.9±25.9 °C

Names

Name	pergolide
Synonym	More Synonyms

Pergolide BiologicalActivity

Description	Pergolide (LY127809 (free base)) is an ergot-derived orally active dopamine receptor agonist. Pergolide can be used for Parkinson disease research[1].
Related Catalog	Signaling Pathways >>GPCR/G Protein >>Dopamine ReceptorSignaling Pathways >>Neuronal Signaling >>Dopamine ReceptorResearch Areas >>Neurological Disease
References	[1]. Van Camp G, et al. Treatment of Parkinson's disease with pergolide and relation to restrictive valvular heart disease. Lancet. 2004 Apr 10;363(9416):1179-83.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	491.3±35.0 °C at 760 mmHg
Melting Point	207.5ºC
Molecular Formula	C₁₉H₂₆N₂S
Molecular Weight	314.488
Flash Point	250.9±25.9 °C
Exact Mass	314.181671
PSA	44.33000
LogP	4.49
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.614
InChIKey	YEHCICAEULNIGD-MZMPZRCHSA-N
SMILES	CCCN1CC(CSC)CC2c3cccc4[nH]cc(c34)CC21

Safety Information

RIDADR	UN 1544 6.1/PG II
RTECS	KE6344964
Packaging Group	II

Synonyms

pergolida

(6aR,9R,10aR)-9-[(methylsulfanyl)methyl]-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline

Permax (TN)

(8b)-8-[(Methylthio)methyl]-6-propylergoline

Pergolidum [INN-Latin]

(6aR,9R,10aR)-9-(Methylthiomethyl)-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline

D-6-n-Propyl-8b-methylmercaptomethylergoline

Ly 141B

(6aR,9R,10aR)-9-[(Methylsulfanyl)methyl]-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]chinolin

8β-[(Methylthio)methyl]-6-propylergoline

Permax

Ergoline, 8-[(methylthio)methyl]-6-propyl-, (8β)-

Pergolide

Pergolidum

Pergolida [INN-Spanish]

(6aR,9R,10aR)-9-(methylsulfanylmethyl)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline

Ergoline, 8-((methylthio)methyl)-6-propyl-, (8β)-

UNII-24MJ822NZ9

Pergolide (INN)

(8β)-8-[(methylthio)methyl]-6-propylergoline

(8β)-8-[(Methylsulfanyl)methyl]-6-propylergoline

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