CAS 95-70-5|2,5-Diaminotoluene

Introduction：Basic information about CAS 95-70-5|2,5-Diaminotoluene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	2,5-Diaminotoluene
CAS Number	95-70-5	Molecular Weight	122.168
Density	1.1±0.1 g/cm3	Boiling Point	273.7±20.0 °C at 760 mmHg
Molecular Formula	C₇H₁₀N₂	Melting Point	64°C
MSDS	/	Flash Point	140.6±21.3 °C

Names

Name	2-methyl-1,4-phenylenediamine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	273.7±20.0 °C at 760 mmHg
Melting Point	64°C
Molecular Formula	C₇H₁₀N₂
Molecular Weight	122.168
Flash Point	140.6±21.3 °C
Exact Mass	122.084396
PSA	52.04000
LogP	-0.22
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.636
InChIKey	OBCSAIDCZQSFQH-UHFFFAOYSA-N
SMILES	Cc1cc(N)ccc1N

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XS9700000

CHEMICAL NAME :: Toluene-2,5-diamine

CAS REGISTRY NUMBER :: 95-70-5

BEILSTEIN REFERENCE NO. :: 0774521

LAST UPDATED :: 199710

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C7-H10-N2

MOLECULAR WEIGHT :: 122.19

WISWESSER LINE NOTATION :: ZR DZ B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 102 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Skin and Appendages - hair

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 625 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 222 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1400 mg/kg/14D-I

TOXIC EFFECTS :: Liver - changes in liver weight Immunological Including Allergic - decrease in humoral immune response Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - hamster Liver

DOSE/DURATION :: 10 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 136,255,1984 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,97,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,97,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

Hazard Codes	T: Toxic;N: Dangerous for the environment;
Risk Phrases	R20/21
Safety Phrases	S24-S37-S45-S61
RIDADR	2811
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2921519090

Customs

HS Code	2921519090
Summary	2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

MFCD00035779

2-Methyl-1,4-benzenediamine

1,4-Diamino-2-methylbenzene

2-Methylbenzene-1,4-diamine

ZR DZ B1

1,4-Benzenediamine, 2-methyl-

2,5-Diaminotoluene

EINECS 202-442-1

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