CAS 6873-13-8|Phellodendrine

Introduction：Basic information about CAS 6873-13-8|Phellodendrine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Phellodendrine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Phellodendrine
CAS Number	6873-13-8	Molecular Weight	377.862
Density	/	Boiling Point	/
Molecular Formula	C₂₀H₂₄NO₄	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	(7S,13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,11-diol
Synonym	More Synonyms

Phellodendrine BiologicalActivity

Description	Phellodendrine, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendri chinensis cortex. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect [1].
Related Catalog	Signaling Pathways >>PI3K/Akt/mTOR >>Akt
Target	Akt NF-κB
References	[1]. Li L , et al. The defensive effect of phellodendrine against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway in zebrafish embryos. Life Sci. 2016 Jul 15;157:97-106.

Chemical & Physical Properties

Molecular Formula	C₂₀H₂₄NO₄
Molecular Weight	377.862
Exact Mass	377.139374
PSA	58.92000
LogP	2.87390
InChIKey	RBBVPNQTBKHOEQ-KKSFZXQISA-O
SMILES	COc1cc2c(cc1O)CC1c3cc(O)c(OC)cc3CC[N+]1(C)C2

Synonyms

OB-5 Compound

Phellodendrin

2,11-dihydroxy-3,10-dimethoxy-7-methyl-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinolinium

6H-Dibenzo(a,g)quinolizinium,5,8,13,13a-tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7-methyl-,(7S-cis)

6H-Dibenzo[a,g]quinolizinium, 5,8,13,13a-tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7-methyl-, chloride, (13aS)- (1:1)

Phallodendrin

Phellodendrine

(13aS)-2,11-Dihydroxy-3,10-dimethoxy-7-methyl-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolinium chloride

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