CAS 99590-86-0|EGTA-AM

Introduction：Basic information about CAS 99590-86-0|EGTA-AM, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. EGTA-AM BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	EGTA-AM
CAS Number	99590-86-0	Molecular Weight	668.59800
Density	1.303g/cm3	Boiling Point	664.2ºC at 760 mmHg
Molecular Formula	C₂₆H₄₀N₂O₁₈	Melting Point	/
MSDS	/	Flash Point	355.5ºC

Names

Name	acetyloxymethyl 2-[[2-(acetyloxymethoxy)-2-oxoethyl]-[2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]ethoxy]ethoxy]ethyl]amino]acetate
Synonym	More Synonyms

EGTA-AM BiologicalActivity

Description	EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca2+ chelator with slow chelating dynamics.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Neurological DiseaseBiochemical Assay Reagents
In Vitro	EGTA-AM (50 μM) markedly reduces the asynchronous excitatory postsynaptic currents (aEPSC) to 58.9 ± 8.1% of the control level, but only reduces the synchronous excitatory postsynaptic currents (EPSCs), measured as charge transfer produced by the stimulation train[1].
References	[1]. Li MJ, et al. Cholinergic and glutamatergic transmission at synapses between pedunculopotine tegmental nucleus axonal terminals and A7 catecholamine cell group noradrenergic neurons in the rat. Neuropharmacology. 2016 Nov;110(Pt A):237-50

Chemical & Physical Properties

Density	1.303g/cm3
Boiling Point	664.2ºC at 760 mmHg
Molecular Formula	C₂₆H₄₀N₂O₁₈
Molecular Weight	668.59800
Flash Point	355.5ºC
Exact Mass	668.22800
PSA	235.34000
Index of Refraction	1.487
InChIKey	GNJXVFXIDHCCKR-UHFFFAOYSA-N
SMILES	CC(=O)OCOC(=O)CN(CCOCCOCCN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O

Synonyms

EGTA acetoxymethyl ester

Egta-AME

EGTA/AM

EGTA-AM

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