CAS 23601-40-3|2,5,8,11,14,17-Hexaoxanonadecan-19-ol

Introduction:Basic information about CAS 23601-40-3|2,5,8,11,14,17-Hexaoxanonadecan-19-ol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2,5,8,11,14,17-Hexaoxanonadecan-19-ol
CAS Number23601-40-3Molecular Weight296.357
Density1.1±0.1 g/cm3Boiling Point375.6±37.0 °C at 760 mmHg
Molecular FormulaC13H28O7Melting Point/
MSDS/Flash Point180.9±26.5 °C

Names

Namehexaethylene glycol monomethyl ether
SynonymMore Synonyms

2,5,8,11,14,17-Hexaoxanonadecan-19-ol BiologicalActivity

DescriptionHexaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point375.6±37.0 °C at 760 mmHg
Molecular FormulaC13H28O7
Molecular Weight296.357
Flash Point180.9±26.5 °C
Exact Mass296.183502
PSA75.61000
LogP-2.59
Vapour Pressure0.0±1.9 mmHg at 25°C
Index of Refraction1.446
InChIKeyFHHGCKHKTAJLOM-UHFFFAOYSA-N
SMILESCOCCOCCOCCOCCOCCOCCO

Safety Information

Hazard CodesXi
HS Code2909499000

Customs

HS Code2909499000
Summary2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Synonyms

2,5,8,11,14,17-Hexaoxanonadecan-19-ol
hexa-PEG monomethyl ether
methoxy polyethyleneglycol tosylate
methoxyhexaethylene glycol
EINECS 245-775-8
2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
3,6,9,12,15,18-Hexaoxanonadecan-1-ol
Hexaethylene glycol monomethyl ether
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