Introduction：Basic information about CAS 2328-12-3|6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride |
|---|
| CAS Number | 2328-12-3 | Molecular Weight | 229.703 |
|---|
| Density | 1.071g/cm3 | Boiling Point | 314.9ºC at 760 mmHg |
|---|
| Molecular Formula | C11H16ClNO2 | Melting Point | 260-265 °C(lit.) |
|---|
| MSDS | / | Flash Point | 124.7ºC |
|---|
Names
| Name | 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline,hydrochloride |
|---|
| Synonym | More Synonyms |
|---|
Chemical & Physical Properties
| Density | 1.071g/cm3 |
|---|
| Boiling Point | 314.9ºC at 760 mmHg |
|---|
| Melting Point | 260-265 °C(lit.) |
|---|
| Molecular Formula | C11H16ClNO2 |
|---|
| Molecular Weight | 229.703 |
|---|
| Flash Point | 124.7ºC |
|---|
| Exact Mass | 229.086960 |
|---|
| PSA | 30.49000 |
|---|
| LogP | 2.48030 |
|---|
| Vapour Pressure | 0.000451mmHg at 25°C |
|---|
| InChIKey | SHOWAGCIRTUYNA-UHFFFAOYSA-N |
|---|
| SMILES | COc1cc2c(cc1OC)CNCC2.Cl |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- NX5017980
- CHEMICAL NAME :
- Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride
- CAS REGISTRY NUMBER :
- 2328-12-3
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C11-H15-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 229.73
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 272 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 88,1197,1968
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 62,165,1938
|
Safety Information
| Hazard Codes | Xi:Irritant; |
|---|
| Risk Phrases | R36/37/38 |
|---|
| Safety Phrases | S26-S36 |
|---|
| WGK Germany | 3 |
|---|
| RTECS | NX5017980 |
|---|
| HS Code | 2933499090 |
|---|
Customs
| HS Code | 2933499090 |
|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1) |
| EINECS 251-223-7 |
| 6,7-dimethoxy-1,2,3,4-tetrahydroisochinoline hydrochloride |
| MFCD00012744 |
| 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline Hydrochloride |
| 1,2,3,4-Tetrahydro-6,7-dimethoxyisoquinoline hydrochloride |
| Heliamine hydrochloride |
| 6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride |
| Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1) |
| 1,2,3,4-tetrahydro-6,7-dimethoxylsoquinoline hydrochloride |
| 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline,chloride |
| 1,2,3,4-tetrahydro-6,7-dimethoxy-,hydrochloride |
