Introduction：Basic information about CAS 112465-94-8|U-54494A HYDROCHLORIDE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | U-54494A HYDROCHLORIDE |
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| CAS Number | 112465-94-8 | Molecular Weight | 391.76 |
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| Density | / | Boiling Point | 496.5ºC at 760 mmHg |
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| Molecular Formula | C18H25Cl3N2O | Melting Point | / |
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| MSDS | / | Flash Point | 254.1ºC |
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Names
| Name | 3,4-dichloro-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)benzamide,hydrochloride |
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| Synonym | More Synonyms |
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U-54494A HYDROCHLORIDE BiologicalActivity
| Description | U-54494A is a benzamide derivative related to κ-opioid receptor agonists, U-54494A has an anticonvulsant activity[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Opioid ReceptorSignaling Pathways >>Neuronal Signaling >>Opioid ReceptorResearch Areas >>Neurological Disease |
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| References | [1]. Fischer, et, al. Anticonvulsant and related effects of U-54494A in various seizure tests. J Pharmacol Exp Ther. 1993, 267, 1. [2]. G De Sarro, et, al. Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex. Gen Pharmacol. 1993, 24, 2. |
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Chemical & Physical Properties
| Boiling Point | 496.5ºC at 760 mmHg |
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| Molecular Formula | C18H25Cl3N2O |
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| Molecular Weight | 391.76 |
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| Flash Point | 254.1ºC |
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| Exact Mass | 390.10300 |
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| PSA | 23.55000 |
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| LogP | 5.21230 |
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| Vapour Pressure | 5.38E-10mmHg at 25°C |
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| InChIKey | WFUASZXAHZXJMX-PPPUBMIESA-N |
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| SMILES | CN(C(=O)c1ccc(Cl)c(Cl)c1)C1CCCCC1N1CCCC1.Cl |
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Synonyms
