CAS 85392-79-6|Indanidine

Introduction:Basic information about CAS 85392-79-6|Indanidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameIndanidine
CAS Number85392-79-6Molecular Weight215.25400
Density1.4g/cm3Boiling Point413.3ºC at 760 mmHg
Molecular FormulaC11H13N5Melting Point/
MSDS/Flash Point203.8ºC

Names

NameIndanidine
SynonymMore Synonyms

Indanidine BiologicalActivity

DescriptionIndanidine is an alpha-adrenergic agonist.
Related CatalogSignaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Cardiovascular Disease
Target

alpha-adrenergic[1]

In VivoThe selective alpha 1-adrenoceptor agonist, Indanidine, also behaved as a partial agonist in the aorta and produced no significant contractions of the small mesenteric artery. Since Idazoxan and Indanidine have been reported to raise blood pressure in the pithed rat via an action at vascular alpha 1-adrenoceptors, these results call into question the reliability of the small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity in vivo[1].
References

[1]. Van der Graaf PH, et al. Analysis of the action of idazoxan calls into question the reliability of the rat isolated small mesenteric artery assay as a predictor for alpha 1-adrenoceptor-mediated pressor activity. Naunyn Schmiedebergs Arch Pharmacol. 1996 Aug-Sep;354(3):389-92.

Chemical & Physical Properties

Density1.4g/cm3
Boiling Point413.3ºC at 760 mmHg
Molecular FormulaC11H13N5
Molecular Weight215.25400
Flash Point203.8ºC
Exact Mass215.11700
PSA54.24000
LogP0.78180
Index of Refraction1.738
InChIKeyPNHJTLDBYZVCGW-UHFFFAOYSA-N
SMILESCn1cc2c(NC3=NCCN3)cccc2n1
Storage condition2-8℃

Safety Information

HS Code2933990090

Customs

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Indanidinum
Unii-mp564ife34
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