CAS 22881-35-2|Famprofazone

Introduction:Basic information about CAS 22881-35-2|Famprofazone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameFamprofazone
CAS Number22881-35-2Molecular Weight377.52200
Density1.083g/cm3Boiling Point485.1ºC at 760mmHg
Molecular FormulaC24H31N3OMelting Point/
MSDSChineseUSAFlash Point184.8ºC
Symbol
GHS07
Signal WordWarning

Names

Name1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one
SynonymMore Synonyms

Chemical & Physical Properties

Density1.083g/cm3
Boiling Point485.1ºC at 760mmHg
Molecular FormulaC24H31N3O
Molecular Weight377.52200
Flash Point184.8ºC
Exact Mass377.24700
PSA30.17000
LogP4.36240
Vapour Pressure1.45E-09mmHg at 25°C
Index of Refraction1.574
InChIKeyGNUXVOXXWGNPIV-UHFFFAOYSA-N
SMILESCC(C)c1c(CN(C)C(C)Cc2ccccc2)n(C)n(-c2ccccc2)c1=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ9451000
CHEMICAL NAME :
Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)m ethylamino)methyl-
CAS REGISTRY NUMBER :
22881-35-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C24-H31-N3-O
MOLECULAR WEIGHT :
377.58
WISWESSER LINE NOTATION :
T5NNVJ A1 BR& DY1&1 E1N1&Y1&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co., Steintorst 13, 4010 Basel, Switzerland) V.50- 1920- Volume(issue)/page/year: 84,351,1954

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH302
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn: Harmful;
Risk Phrases22
Safety Phrases36
RIDADRNONH for all modes of transport
WGK Germany3
RTECSUQ9451000

Articles14

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Illegal or legitimate use? Precursor compounds to amphetamine and methamphetamine.

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The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution...

Detection and identification of famprofazone and its metabolite in human urine.

J. Chromatogr. B, Biomed. Appl. 661(2) , 255-61, (1994)

Detection and identification of famprofazone and its metabolite, p-hydroxydesmethylfamprofazone, were described. The identity of the new metabolite was confirmed by comparing its mass spectrum and gas...

Urinary methamphetamine concentration following famprofazone administration.

J. Anal. Toxicol. 18(5) , 265-8, (1994)

A 37-year-old man had a considerable concentration of methamphetamine in his urine, but he denied taking any abused drug. It was found that he took a pain killer that contains famprofazone, a relative...

Synonyms

Famprofazone
Famprofazona [INN-Spanish]
Famprofazonum [INN-Latin]
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