CAS 5251-34-3|cloprednol

Introduction:Basic information about CAS 5251-34-3|cloprednol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namecloprednol
CAS Number5251-34-3Molecular Weight392.87300
Density1.4g/cm3Boiling Point600.3ºC at 760mmHg
Molecular FormulaC21H25ClO5Melting Point/
MSDS/Flash Point316.9ºC

Names

Name(8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
SynonymMore Synonyms

cloprednol BiologicalActivity

DescriptionCloprednol is an orally active synthetic glucocorticoid. Cloprednol has anti-inflammatory activity, and can be used in the research of asthma[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References

[1]. Gavani UD, et al. Long-term cloprednol use in chronic asthma. JAMA. 1979 Dec 14;242(24):2679-82.  

Chemical & Physical Properties

Density1.4g/cm3
Boiling Point600.3ºC at 760mmHg
Molecular FormulaC21H25ClO5
Molecular Weight392.87300
Flash Point316.9ºC
Exact Mass392.13900
PSA94.83000
LogP1.90010
Index of Refraction1.635
InChIKeyYTJIBEDMAQUYSZ-FDNPDPBUSA-N
SMILESCC12C=CC(=O)C=C1C(Cl)=CC1C2C(O)CC2(C)C1CCC2(O)C(=O)CO

Synonyms

CLOPREDNOL
Cloradryn
Cloprednole
Syntestan
Novacort
Cloprednolum
Synestan
RS 4691
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