Introduction：Basic information about CAS 42061-52-9|Pumitepa, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Pumitepa |
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| CAS Number | 42061-52-9 | Molecular Weight | 322.30600 |
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| Density | 1.7g/cm3 | Boiling Point | 528.7ºC at 760mmHg |
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| Molecular Formula | C12H19N8OP | Melting Point | / |
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| MSDS | / | Flash Point | 273.5ºC |
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Names
| Name | Pumitepa |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.7g/cm3 |
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| Boiling Point | 528.7ºC at 760mmHg |
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| Molecular Formula | C12H19N8OP |
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| Molecular Weight | 322.30600 |
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| Flash Point | 273.5ºC |
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| Exact Mass | 322.14200 |
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| PSA | 91.77000 |
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| LogP | 0.52930 |
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| Index of Refraction | 1.828 |
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| InChIKey | KAEVHZSIYLATMK-UHFFFAOYSA-N |
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| SMILES | CN(C)c1nc(NP(=O)(N2CC2)N2CC2)c2c(ncn2C)n1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- SZ5827000
- CHEMICAL NAME :
- Phosphinic amide, P,P-bis(1-aziridinyl)-N-(2-(dimethylamino)-7-methyl-7 H-purin-6-yl)-
- CAS REGISTRY NUMBER :
- 42061-52-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C12-H19-N8-O-P
- MOLECULAR WEIGHT :
- 322.36
- WISWESSER LINE NOTATION :
- T56 BN DN FN HNJ B1 GN1&1 IMPO&- AT3NTJ&- AT3NTJ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 175 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 24 mg/kg
- REFERENCE :
- BEBMAE Byulleten' Eksperimental'noi Biologii i Meditsiny. Bulletin of Experimental Biology and Medicine. For English translation, see BEXBAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 102(7),76,1986
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Synonyms
| <32P>-Fopunic |
| 6-Diethylenimidophosphoamido-2-dimethylamino-7-methylpurin |
| bis-aziridin-1-yl-phosphinic acid 2-dimethylamino-7-methyl-7H-purin-6-ylamide |
| Bis(1-aziridinyl)[[2-(dimethylamino)-7-methyl-7H-purin-6-yl]amino]phosphine oxide |
