CAS 211690-33-4|lomefloxacin, aspartate

Introduction:Basic information about CAS 211690-33-4|lomefloxacin, aspartate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namelomefloxacin, aspartate
CAS Number211690-33-4Molecular Weight484.451
Density/Boiling Point/
Molecular FormulaC21H26F2N4O7Melting Point/
MSDS/Flash Point/

Names

Name(2S)-2-aminobutanedioic acid,1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
SynonymMore Synonyms

lomefloxacin, aspartate BiologicalActivity

DescriptionLomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibacterial agent. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc.[1][2].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
Target

MIC90: 0.12 mg/L (Haemophilus influenzae), 0.25 mg/L (Moraxella catarrhalis), 0.06 mg/L (Legionella pneumophila)[1]

References

[1]. Hoogkamp-Korstanje JA. In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections. J Antimicrob Chemother. 1997 Sep;40(3):427-31.

[2]. Reem I Al-Wabli. Lomefloxacin. Profiles Drug Subst Excip Relat Methodol. 2017;42:193-240.

Chemical & Physical Properties

Molecular FormulaC21H26F2N4O7
Molecular Weight484.451
Exact Mass484.176941
PSA175.19000
LogP1.76300
InChIKeyYCOJCBAVYZZKRS-WNQIDUERSA-N
SMILESCCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c21.NC(CC(=O)O)C(=O)O
Storage condition-20°C Freezer

Synonyms

I06-2220
DM 10 L-Aspartate
(S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (1:1)
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, compd. with L-aspartic acid (1:1)
Lomefloxacin Aspartate
1-Ethyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid - L-aspartic acid (1:1)
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