Introduction:Basic information about CAS 211690-33-4|lomefloxacin, aspartate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | lomefloxacin, aspartate |
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| CAS Number | 211690-33-4 | Molecular Weight | 484.451 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C21H26F2N4O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (2S)-2-aminobutanedioic acid,1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid |
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| Synonym | More Synonyms |
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lomefloxacin, aspartate BiologicalActivity
| Description | Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibacterial agent. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc.[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | MIC90: 0.12 mg/L (Haemophilus influenzae), 0.25 mg/L (Moraxella catarrhalis), 0.06 mg/L (Legionella pneumophila)[1] |
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| References | [1]. Hoogkamp-Korstanje JA. In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections. J Antimicrob Chemother. 1997 Sep;40(3):427-31. [2]. Reem I Al-Wabli. Lomefloxacin. Profiles Drug Subst Excip Relat Methodol. 2017;42:193-240. |
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Chemical & Physical Properties
| Molecular Formula | C21H26F2N4O7 |
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| Molecular Weight | 484.451 |
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| Exact Mass | 484.176941 |
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| PSA | 175.19000 |
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| LogP | 1.76300 |
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| InChIKey | YCOJCBAVYZZKRS-WNQIDUERSA-N |
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| SMILES | CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c21.NC(CC(=O)O)C(=O)O |
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| Storage condition | -20°C Freezer |
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Synonyms
| I06-2220 |
| DM 10 L-Aspartate |
| (S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (1:1) |
| 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, compd. with L-aspartic acid (1:1) |
| Lomefloxacin Aspartate |
| 1-Ethyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid - L-aspartic acid (1:1) |