Introduction：Basic information about CAS 83-95-4|Skimmianin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Skimmianin |
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| CAS Number | 83-95-4 | Molecular Weight | 259.257 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 401.6±40.0 °C at 760 mmHg |
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| Molecular Formula | C14H13NO4 | Melting Point | 178° |
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| MSDS | / | Flash Point | 196.7±27.3 °C |
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Names
| Name | 4,7,8-trimethoxyfuro[2,3-b]quinoline |
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| Synonym | More Synonyms |
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Skimmianin BiologicalActivity
| Description | Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with analgesic, antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Huang A, et al. Metabolic Profile of Skimmianine in Rats Determined by Ultra-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry. Molecules. 2017 Mar 23;22(4). |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 401.6±40.0 °C at 760 mmHg |
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| Melting Point | 178° |
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| Molecular Formula | C14H13NO4 |
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| Molecular Weight | 259.257 |
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| Flash Point | 196.7±27.3 °C |
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| Exact Mass | 259.084473 |
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| PSA | 53.72000 |
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| LogP | 2.86 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.621 |
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| InChIKey | SLSIBLKBHNKZTB-UHFFFAOYSA-N |
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| SMILES | COc1ccc2c(OC)c3ccoc3nc2c1OC |
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| Storage condition | 2-8C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LV2800000
- CHEMICAL NAME :
- Furo(2,3-b)quinoline, 4,7,8-trimethoxy-
- CAS REGISTRY NUMBER :
- 83-95-4
- BEILSTEIN REFERENCE NO. :
- 0028904
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C14-H13-N-O4
- MOLECULAR WEIGHT :
- 259.28
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 5 ug/plate
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 34,1826,1986
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| skimmiamine |
| 7,8-Dimethoxydictamnine |
| Skimmianine |
| b-fagarine |
| β-Fagarine |
| Chloroxylonine |
| 4,7,8-Trimethoxyfuro[2,3-b]quinoline |
| Skimmianin |
| Furo[2,3-b]quinoline, 4,7,8-trimethoxy- |
