CAS 76410-58-7|4-Borono-L-phenylalanine
Introduction：Basic information about CAS 76410-58-7|4-Borono-L-phenylalanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Borono-L-phenylalanine | ||
|---|---|---|---|
| CAS Number | 76410-58-7 | Molecular Weight | 209.01 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 449.3±55.0 °C at 760 mmHg |
| Molecular Formula | C9H12BNO4 | Melting Point | 285-293ºC (dec.) |
| MSDS | ChineseUSA | Flash Point | 225.5±31.5 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 4-Borono-L-phenylalanine |
|---|---|
| Synonym | More Synonyms |
4-Borono-L-phenylalanine BiologicalActivity
| Description | (S)-2-Amino-3-(4-boronophenyl)propanoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 449.3±55.0 °C at 760 mmHg |
| Melting Point | 285-293ºC (dec.) |
| Molecular Formula | C9H12BNO4 |
| Molecular Weight | 209.01 |
| Flash Point | 225.5±31.5 °C |
| Exact Mass | 209.085938 |
| PSA | 103.78000 |
| LogP | 0.49 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.591 |
| InChIKey | NFIVJOSXJDORSP-QMMMGPOBSA-N |
| SMILES | NC(Cc1ccc(B(O)O)cc1)C(=O)O |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36-37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2931900090 |
Customs
| HS Code | 2931900090 |
|---|---|
| Summary | 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0% |
Articles27
More Articles| Pharmacokinetic analysis and uptake of 18F-FBPA-Fr after ultrasound-induced blood-brain barrier disruption for potential enhancement of boron delivery for neutron capture therapy. J. Nucl. Med. 55(4) , 616-21, (2014) Boronophenylalanine has been applied in clinical boron neutron capture therapy for the treatment of high-grade gliomas. The purpose of this study was to evaluate the pharmacokinetics of 4-borono-2-(18... | |
| Low dose of gamma irradiation enhanced boronophenylalanine uptake in head and neck carcinoma cells for boron neutron capture therapy. Appl. Radiat. Isot. 69(12) , 1728-31, (2011) This study attempted to increase the boron uptake of human head and neck carcinoma SAS cells for BNCT by using a gamma dose of 0.1 Gy for combined treatment. Intracellular boron concentrations in 25 μ... | |
| Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax. BMC Cancer 10 , 661, (2010) Boron neutron capture therapy (BNCT) is an alternative treatment modality for patients with glioma. The aim of this study was to determine whether induction of apoptosis contributes to the main therap... |
Synonyms
| (2S)-2-amino-3-(4-boronophenyl)propanoic acid |
| Phenylalanine, 4-borono- |
| MFCD01075172 |
| 4-(dihydroxyboranyl)-L-phenylalanine |
| L-Phenylalanine, 4-borono- |
| 4-(Dihydroxyboryl)phenylalanine |
| p-Borono-L-phenylalanine |
