Introduction：Basic information about CAS 50-69-1|D-Ribose, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].
Related Catalog
Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
In Vitro
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism[1]. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].
References
[1]. Hong J, et al. D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. Arch Pharm Res. 2018 Aug;41(8):838-847.
Chemical & Physical Properties
Density
1.5±0.1 g/cm3
Boiling Point
415.5±38.0 °C at 760 mmHg
Melting Point
88-92ºC
Molecular Formula
C5H10O5
Molecular Weight
150.13
Flash Point
219.2±23.3 °C
Exact Mass
150.052826
PSA
97.99000
LogP
-2.39
Vapour Pressure
0.0±2.2 mmHg at 25°C
Index of Refraction
1.544
InChIKey
PYMYPHUHKUWMLA-LMVFSUKVSA-N
SMILES
O=CC(O)C(O)C(O)CO
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
VJ2275000
CHEMICAL NAME :
Ribose, D-
CAS REGISTRY NUMBER :
50-69-1
BEILSTEIN REFERENCE NO. :
1723081
LAST UPDATED :
199801
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H10-O5
MOLECULAR WEIGHT :
150.15
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intrauterine
DOSE :
5045 ug/kg
SEX/DURATION :
female 2 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
MUTATION DATA
TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
30 mmol/L
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 180,246,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1001 No. of Facilities: 439 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 4169 (estimated) No. of Female Employees: 2111 (estimated)
2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
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