CAS 203805-96-3|EDTA-d16
Introduction：Basic information about CAS 203805-96-3|EDTA-d16, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | EDTA-d16 | ||
|---|---|---|---|
| CAS Number | 203805-96-3 | Molecular Weight | 308.341 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 614.2±55.0 °C at 760 mmHg |
| Molecular Formula | C10D16N2O8 | Melting Point | / |
| MSDS | / | Flash Point | 325.2±31.5 °C |
Names
| Name | ethylenediaminetetraacetic acid-d16 |
|---|---|
| Synonym | More Synonyms |
EDTA-d16 BiologicalActivity
| Description | Ethylenediaminetetraacetic acid-d16 is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>Others |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9. [3]. Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 200745(5):565-76. [4]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb10(1):58-62. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 614.2±55.0 °C at 760 mmHg |
| Molecular Formula | C10D16N2O8 |
| Molecular Weight | 308.341 |
| Flash Point | 325.2±31.5 °C |
| Exact Mass | 308.191101 |
| PSA | 155.68000 |
| LogP | -0.43 |
| Vapour Pressure | 0.0±3.8 mmHg at 25°C |
| Index of Refraction | 1.580 |
| InChIKey | KCXVZYZYPLLWCC-PZVDDEMOSA-N |
| SMILES | O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O |
Synonyms
| EDTA-d16 |
| 2,2',2'',2'''-[(H)Ethane-1,2-diyldinitrilo]tetra(H)acetic acid |
| 2,2',2'',2'''-[(H)-1,2-Ethanediyldinitrilo]tetra(H)acetic acid |
| Ethylenediaminetetraacetic Acid-d16 |
