Introduction：Basic information about CAS 8015-61-0|Aloin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Aloin |
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| CAS Number | 8015-61-0 | Molecular Weight | 418.394 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 752.6±60.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O9 | Melting Point | / |
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| MSDS | / | Flash Point | 268.0±26.4 °C |
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Names
| Name | (1S)-1,5-Anhydro-1-[(9S)-4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9 ,10-dihydro-9-anthracenyl]-D-glucitol |
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| Synonym | More Synonyms |
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Aloin BiologicalActivity
| Description | Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) has diverse biological activities such as anti-inflammatory, immunity, antidiabetic, antioxidant, antibacterial, antifungal, and antitumor activities. Aloin (mixture of A&B) also an effective inhibitor of stimulated granulocyte matrix metalloproteinases (MMPs)[1][2]. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>MMPSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | MMPs[2] |
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| References | [1]. Jiang M, et al. Evaluation of the Antioxidative, Antibacterial, and Anti-Inflammatory Effects of the Aloe Fermentation Supernatant Containing Lactobacillus plantarum HM218749.1. Mediators Inflamm. 2016;2016:2945650. [2]. Barrantes E, et al. Inhibition of collagenase and metalloproteinases by aloins and aloe gel. Life Sci. 2003 Jan 3;72(7):843-50. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 752.6±60.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O9 |
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| Molecular Weight | 418.394 |
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| Flash Point | 268.0±26.4 °C |
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| Exact Mass | 418.126373 |
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| PSA | 167.91000 |
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| LogP | 1.86 |
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| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
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| Index of Refraction | 1.741 |
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| InChIKey | AFHJQYHRLPMKHU-GCLVLASRSA-N |
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| SMILES | O=C1c2c(O)cccc2C(C2OC(CO)C(O)C(O)C2O)c2cc(CO)cc(O)c21 |
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| Water Solubility | pyridine: 50 mg/mL, clear, dark red |
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26;S36 |
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| WGK Germany | 3 |
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| HS Code | 2938909090 |
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Customs
Synonyms
| (1S)-1,5-Anhydro-1-[(9R)-4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl]-D-glucitol |
| isobarbaloin |
| (10R)-10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone |
| 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-, (R)- |
| 10-(1',5'-Anhydroglucosyl)-aloe-emodin-9-anthrone |
| (10R)-1,8-Dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-9(10H)-anthracenone |
| D-Glucitol, 1,5-anhydro-1-C-[(9R)-9,10-dihydro-4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9-anthracenyl]-, (1S)- |
| (1S)-1,5-Anhydro-1-[(9R)-4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydro-9-anthracenyl]-D-glucitol |
