CAS 56005-10-8|2-HYDROXY-5-METHOXY-3-UNDECYL[1,4]BENZOQUINONE

Introduction：Basic information about CAS 56005-10-8|2-HYDROXY-5-METHOXY-3-UNDECYL[1,4]BENZOQUINONE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	2-HYDROXY-5-METHOXY-3-UNDECYL[1,4]BENZOQUINONE
CAS Number	56005-10-8	Molecular Weight	308.41300
Density	1.06g/cm3	Boiling Point	439.5ºC at 760mmHg
Molecular Formula	C₁₈H₂₈O₄	Melting Point	/
MSDS	/	Flash Point	149.9ºC

Names

Name	5-O-methyl embelin
Synonym	More Synonyms

BiologicalActivity

Description	5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9, low-density lipoprotein receptor (IDOL), and sterol regulatory element binding protein 2 (SREBP2) mRNA expression[1].
Related Catalog	Signaling Pathways >>Metabolic Enzyme/Protease >>Ser/Thr ProteaseResearch Areas >>Cardiovascular Disease
In Vitro	5-O-Methylembelin（compound 3；20 μM；24 小时）显着下调 PCSK9（IC50 值为 4.9 μM）、IDOL 和 SREBP2 mRNA 表达[1]。 RT-PCR[1] Cell Line: HepG2 cells Concentration: 20 μM Incubation Time: 24 h Result: Inhibited PCSK9, IDOL, and SREBP2 mRNA expression.
References	[1]. Pisey Pel, et al. Isocoumarins and Benzoquinones with Their Proprotein Convertase Subtilisin/Kexin Type 9 Expression Inhibitory Activities from Dried Roots of Lysimachia vulgaris. ACS Omega. 2022 Dec 8;7(50):47296-47305.

Chemical & Physical Properties

Density	1.06g/cm3
Boiling Point	439.5ºC at 760mmHg
Molecular Formula	C₁₈H₂₈O₄
Molecular Weight	308.41300
Flash Point	149.9ºC
Exact Mass	308.19900
PSA	63.60000
LogP	4.40150
Index of Refraction	1.505
InChIKey	KHBJLRRAMCJZLZ-UHFFFAOYSA-N
SMILES	CCCCCCCCCCCC1=C(O)C(=O)C=C(OC)C1=O

Safety Information

HS Code	2914690090

Customs

HS Code	2914690090
Summary	2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Synonyms

5-O-Methylembelin

2-hydroxy-5-methoxy-3-undecylcyclohexa-2,5-diene-1,4-dione

Recommended......