Introduction：Basic information about CAS 487-24-1|7-Hydroxy-4'-methoxyflavone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7-Hydroxy-4'-methoxyflavone |
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| CAS Number | 487-24-1 | Molecular Weight | 268.26 |
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| Density | 1.329g/cm3 | Boiling Point | 479.4ºC at 760mmHg |
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| Molecular Formula | C16H12O4 | Melting Point | 263-264ºC |
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| MSDS | / | Flash Point | 183.4ºC |
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Names
| Name | 7-hydroxy-2-(4-methoxyphenyl)chromen-4-one |
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| Synonym | More Synonyms |
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7-Hydroxy-4'-methoxyflavone BiologicalActivity
| Description | Pratol is a potent inhibitor of NF-κB. Pratol significantly reduces NO and prostaglandin PGE2 production without any cytotoxic in LPS-stimulated RAW 264.7 cells. Pratol reduces proinflammatory cytokines. Pratol can be used in study inflammatory diseases and cancer[1]. |
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| Related Catalog | Research Areas >>Inflammation/Immunology |
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| References | [1]. Chung, Y. C. , et al. Anti-inflammatory Effect of Pratol in LPS-stimulated RAW 264.7 Cells via NF-κB Signaling Pathways. Natural Product Communications, 13(5), 1934578X1801300. |
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Chemical & Physical Properties
| Density | 1.329g/cm3 |
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| Boiling Point | 479.4ºC at 760mmHg |
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| Melting Point | 263-264ºC |
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| Molecular Formula | C16H12O4 |
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| Molecular Weight | 268.26 |
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| Flash Point | 183.4ºC |
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| Exact Mass | 266.09400 |
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| PSA | 39.44000 |
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| LogP | 3.77700 |
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| Vapour Pressure | 8.17E-10mmHg at 25°C |
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| Index of Refraction | 1.641 |
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| InChIKey | SQVXWIUVAILQRH-UHFFFAOYSA-N |
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| SMILES | COc1ccc(-c2cc(=O)c3ccc(O)cc3o2)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DJ3100110
- CHEMICAL NAME :
- 4H-1-Benzopyran-4-one, 7-hydroxy-2-(4-methoxyphenyl)-
- CAS REGISTRY NUMBER :
- 487-24-1
- BEILSTEIN REFERENCE NO. :
- 0237239
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H12-O4
- MOLECULAR WEIGHT :
- 268.28
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 38,67,1983
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Safety Information
Synonyms
| Flavone,7-hydroxy-4'-methoxy |
| 7-Hydroxy-4'-methoxyflavone |
| EINECS 207-653-2 |
| 4'-Methoxy-7-hydroxyflavone |
