CAS 2224-10-4|4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid
| Common Name | 4-(N-(Butylcarbamoyl)sulfamoyl)benzoic acid | ||
|---|---|---|---|
| CAS Number | 2224-10-4 | Molecular Weight | 300.33100 |
| Density | 1.337g/cm3 | Boiling Point | / |
| Molecular Formula | C12H16N2O5S | Melting Point | 210-212ºC |
| MSDS | USA | Flash Point | / |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | 4-Carboxy Tolbutamide |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.337g/cm3 |
|---|---|
| Melting Point | 210-212ºC |
| Molecular Formula | C12H16N2O5S |
| Molecular Weight | 300.33100 |
| Exact Mass | 300.07800 |
| PSA | 120.95000 |
| LogP | 3.03540 |
| Index of Refraction | 1.558 |
| InChIKey | GCMVATDSSHTCOS-UHFFFAOYSA-N |
| SMILES | CCCCNC(=O)NS(=O)(=O)c1ccc(C(=O)O)cc1 |
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 41 |
| Safety Phrases | 26-39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2935009090 |
Customs
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
Articles22
More Articles| Liquid chromatography/tandem mass spectrometry method for simultaneous evaluation of activities of five cytochrome P450s using a five-drug cocktail and application to cytochrome P450 phenotyping studies in rats. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 871(1) , 78-89, (2008) A reliable liquid chromatography/tandem mass spectrometry has been developed for simultaneous evaluation of the activities of five cytochrome P450s (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A) in rat ... | |
| Cytochrome P450 2C9 phenotyping using low-dose tolbutamide. Eur. J. Clin. Pharmacol. 60(3) , 165-71, (2004) The hypoglycaemic drug tolbutamide is used for assessment of CYP2C9 activity in vivo. However, therapeutically active doses of 500 mg bear the risk of hypoglycaemia, and a tolbutamide-derived paramete... | |
| Quantitative determination of tolbutamide and its metabolites in human plasma and urine by high-performance liquid chromatography and UV detection. Ther. Drug Monit. 21(6) , 664-71, (1999) An isocratic, high-performance liquid chromatography method has been developed for simultaneous determination of the oral antidiabetic tolbutamide and two of its metabolites, 4-hydroxytolbutamide and ... |
Synonyms
| Carboxytolbutamide |
| N-Butyl-N'-(4-carboxyphenylsulfonyl)urea |
| 4-(butylcarbamoylsulfamoyl)benzoic acid |
