CAS 2741-30-2|Dimethylamino-PEG3

Introduction:Basic information about CAS 2741-30-2|Dimethylamino-PEG3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDimethylamino-PEG3
CAS Number2741-30-2Molecular Weight177.24100
Density/Boiling Point/
Molecular FormulaC8H19NO3Melting Point/
MSDS/Flash Point/

Names

Name2-[2-[2-(dimethylamino)ethoxy]ethoxy]ethanol
SynonymMore Synonyms

Dimethylamino-PEG3 BiologicalActivity

DescriptionDimethylamino-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Molecular FormulaC8H19NO3
Molecular Weight177.24100
Exact Mass177.13600
PSA41.93000
InChIKeyCCTDPTKERPLATF-UHFFFAOYSA-N
SMILESCN(C)CCOCCOCCO

Safety Information

HS Code2922509090

Customs

HS Code2922509090
Summary2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

Kaolizer 23NP
23P
Dimethylaminoethoxyethoxy-ethanol
Ethanol,2-[2-[2-(dimethylamino)ethoxy]ethoxy]
Kaolizer 23
Dimethylaminotriaethylenalkohol
Kaolizer 23P
2-[2-(2-dimethylamino-ethoxy)-ethoxy]-ethanol
1-O<2'-Dimethylaminoethoxyethyl>ethylenglykol
2-{2-[2-(dimethylamino)ethoxy]ethoxy}ethan-1-ol
2-[2-(2-Dimethylamino-aethoxy)-aethoxy]-aethanol
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