CAS 145643-96-5|Cyclocommunol

Introduction:Basic information about CAS 145643-96-5|Cyclocommunol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCyclocommunol
CAS Number145643-96-5Molecular Weight352.337
Density1.5±0.1 g/cm3Boiling Point628.2±55.0 °C at 760 mmHg
Molecular FormulaC20H16O6Melting Point/
MSDS/Flash Point230.5±25.0 °C

Names

NameCyclocommunol
SynonymMore Synonyms

Cyclocommunol BiologicalActivity

DescriptionCyclocommunol is a prenylflavonoid with antityrosinase and antiplatelet activitie, can be solated from breadfruit. Cyclocommunol exerts anti-tumor activity and inhibits the growth of human hepatoma and gastric cancer cells with IC50 values between 16 and 80 µM. Cyclocommunol shows proapoptotic effect on oral squamous cell carcinoma (OSCC)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Tyrosinase
References

[1]. Weng JR, et al. Cyclocommunol induces apoptosis in human oral squamous cell carcinoma partially through a Mcl-1-dependent mechanism. Phytomedicine. 2018 Jan 15;39:25-32.  

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Boiling Point628.2±55.0 °C at 760 mmHg
Molecular FormulaC20H16O6
Molecular Weight352.337
Flash Point230.5±25.0 °C
Exact Mass352.094696
PSA100.13000
LogP3.51
Vapour Pressure0.0±1.9 mmHg at 25°C
Index of Refraction1.732
InChIKeyVHNPAPHWKVLGHG-UHFFFAOYSA-N
SMILESCC(C)=CC1Oc2cc(O)ccc2-c2oc3cc(O)cc(O)c3c(=O)c21

Safety Information

Hazard CodesXi

Synonyms

6H,7H-[1]Benzopyrano[4,3-b][1]benzopyran-7-one, 3,8,10-trihydroxy-6-(2-methyl-1-propen-1-yl)-
3,8,10-Trihydroxy-6-(2-methyl-1-propen-1-yl)-6H,7H-chromeno[4,3-b]chromen-7-one
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