Introduction：Basic information about CAS 531-75-9|Esculin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Esculin |
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| CAS Number | 531-75-9 | Molecular Weight | 340.29 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 697.7±55.0 °C at 760 mmHg |
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| Molecular Formula | C15H16O9 | Melting Point | 203 °C |
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| MSDS | USA | Flash Point | 262.8±25.0 °C |
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Names
| Name | esculin |
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| Synonym | More Synonyms |
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Esculin BiologicalActivity
| Description | Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti‑oxidative stress and anti‑inflammatory effects, via the MAPK signaling pathway[2]. |
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| Related Catalog | Research Areas >>Cancer |
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| Target | p38 MAPK |
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| References | [1]. Knox K, et al. The Coumarin Glucoside, Esculin, Reveals Rapid Changes in Phloem-Transport Velocity in Response to Environmental Cues. Plant Physiol. 2018 Oct;178(2):795-807. [2]. Song Y, et al. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy and induces anti-oxidative stress and anti-inflammatory effects via the MAPK pathway. Mol Med Rep. 2018 May;17(5):7395-7402. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 697.7±55.0 °C at 760 mmHg |
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| Melting Point | 203 °C |
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| Molecular Formula | C15H16O9 |
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| Molecular Weight | 340.29 |
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| Flash Point | 262.8±25.0 °C |
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| PSA | 149.82000 |
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| LogP | -1.52 |
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| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
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| Index of Refraction | 1.689 |
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| InChIKey | XHCADAYNFIFUHF-TVKJYDDYSA-N |
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| SMILES | O=c1ccc2cc(OC3OC(CO)C(O)C(O)C3O)c(O)cc2o1 |
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| Water Solubility | MODERATELY SOLUBLE |
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Safety Information
| Hazard Codes | F,C,Xi |
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| Risk Phrases | R11 |
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| Safety Phrases | S26-S36/37/39-S45-S24/25 |
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| RIDADR | UN 2924 3/PG 2 |
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| WGK Germany | 3 |
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| RTECS | DJ3085000 |
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| HS Code | 2942000000 |
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Customs
Synonyms
| Crataegin |
| 7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside |
| EINECS 208-517-5 |
| Enallachrome |
| vitaminc2 |
| Esculetin 6-β-D-glucoside |
| POLYDROM |
| Bicolorin |
| Esculetin 6-O-glucoside |
| Polychrom |
| 7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside |
| BICOLOIN |
| 7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate |
| Esculin |
| 7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen-2-one |
| Polychrome |
| 6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one |
| Esculetin 6-b-D-glucoside |
| 2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy- |
| 7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1) |
| Aesculin |
| MFCD00006879 |
| Esculetin-6-O-glucoside |
| 2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-, hydrate (1:1) |
| Escosyl |
