Introduction：Basic information about CAS 80154-34-3|Helicid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Helicid |
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| CAS Number | 80154-34-3 | Molecular Weight | 284.26 |
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| Density | 1.5±0.1 g/cm3 | Boiling Point | 559.9±50.0 °C at 760 mmHg |
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| Molecular Formula | C13H16O7 | Melting Point | 199-200°C |
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| MSDS | / | Flash Point | 215.8±23.6 °C |
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Names
| Name | Helicid |
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| Synonym | More Synonyms |
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Helicid BiologicalActivity
| Description | Helicid (Helicide, Helicidum, 4-Formylphenyl-β-D-allopyranoside) is a major constituent of Helicia nilgirica Bedd. Helicid has been used to treat psychoneurosis for its sedative-hypnotic and analgesic properties[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| In Vivo | Helicid (8-32 mg/kg; given i.g.; once daily for 6 weeks) significantly reverses chronic unpredictable mild stress (CUMS)-induced depression-like behaviors in rats[1]. Animal Model: CUMS-induced depression rat model[1] Dosage: 8 mg/kg, 16 mg/kg, 32 mg/kg Administration: Given i.g.; once daily for 6 weeks Result: Improved CUMS-induced depression-like behavior in rats. |
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| References | [1]. Tong J, et al. Antidepressant effect of helicid in chronic unpredictable mild stress model in rats. Int Immunopharmacol. 2019 Feb;67:13-21. |
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Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 559.9±50.0 °C at 760 mmHg |
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| Melting Point | 199-200°C |
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| Molecular Formula | C13H16O7 |
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| Molecular Weight | 284.26 |
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| Flash Point | 215.8±23.6 °C |
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| Exact Mass | 284.089600 |
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| PSA | 116.45000 |
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| LogP | -1.04 |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.651 |
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| InChIKey | OLZAGZCCJJBKNZ-SYLRKERUSA-N |
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| SMILES | O=Cc1ccc(OC2OC(CO)C(O)C(O)C2O)cc1 |
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Safety Information
| Hazard Codes | Xi |
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| Safety Phrases | S26-S36/37/39-S45-S27 |
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| RIDADR | 3265 |
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| Packaging Group | III |
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| Hazard Class | 8 |
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| HS Code | 2932999099 |
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Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 2-formylphenyl beta-L-glucopyranoside |
| MFCD00210992 |
| HILICIDUM |
| HEARTLEAFHOUTTUYNIAP.E. |
| Benzaldehyde, 4-(β-D-glucopyranosyloxy)- |
| Gynostemma |
| 4-Formylphenyl β-D-glucopyranoside |
| Hiliedum |
| HELICIDUM |
| HELICIDE |
| Benzaldehyde, 4-(β-D-allopyranosyloxy)- |
| Helicid |
| 4-Formylphenyl β-D-allopyranoside |
| 4-Formylphenylb-D-allopyranoside |
