CAS 572-30-5|Avicularin

Introduction：Basic information about CAS 572-30-5|Avicularin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Avicularin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles12
6. Synonyms

Common Name	Avicularin
CAS Number	572-30-5	Molecular Weight	434.350
Density	1.9±0.1 g/cm3	Boiling Point	855.4±65.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₈O₁₁	Melting Point	240-243ºC
MSDS	ChineseUSA	Flash Point	305.8±27.8 °C

Names

Name	avicularin
Synonym	More Synonyms

Avicularin BiologicalActivity

Description	Avicularin is a bio-active flavonoid from plants, anti-inflammatory, anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities. Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF κB (p65), COX 2 and PPAR γ activities[1][2].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Vo VA, et al. Avicularin Inhibits Lipopolysaccharide-Induced Inflammatory Response by Suppressing ERK Phosphorylation in RAW 264.7 Macrophages. Biomol Ther (Seoul). 2012 Nov;20(6):532-7. [2]. Wang Z, et al. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF‑κB/COX‑2/PPAR‑γ activities. Mol Med Rep. 2019 Jun;19(6):5417-5423.

Description

Avicularin is a bio-active flavonoid from plants, anti-inflammatory, anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities. Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF κB (p65), COX 2 and PPAR γ activities[1][2].

Related Catalog

Research Areas >>CancerSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology

References

[1]. Vo VA, et al. Avicularin Inhibits Lipopolysaccharide-Induced Inflammatory Response by Suppressing ERK Phosphorylation in RAW 264.7 Macrophages. Biomol Ther (Seoul). 2012 Nov;20(6):532-7.

[2]. Wang Z, et al. Avicularin ameliorates human hepatocellular carcinoma via the regulation of NF‑κB/COX‑2/PPAR‑γ activities. Mol Med Rep. 2019 Jun;19(6):5417-5423.

Chemical & Physical Properties

Density	1.9±0.1 g/cm3
Boiling Point	855.4±65.0 °C at 760 mmHg
Melting Point	240-243ºC
Molecular Formula	C₂₀H₁₈O₁₁
Molecular Weight	434.350
Flash Point	305.8±27.8 °C
Exact Mass	434.084900
PSA	190.28000
LogP	2.06
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.802
InChIKey	BDCDNTVZSILEOY-UXYNSRGZSA-N
SMILES	O=c1c(OC2OC(CO)C(O)C2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12
Storage condition	2-8C

Safety Information

RIDADR	NONH for all modes of transport

Articles12

Protective effect of components isolated from Lindera erythrocarpa against oxidative stress-induced apoptosis of H9c2 cardiomyocytes.

Phytother Res. 25(11) , 1612-7, (2011)

Eight compounds were isolated from the methanol fraction of Lindera erythrocarpa and assessed for their ability to protect H9c2 cardiomyocytes against oxidative stress-induced cell death. Three of the...

Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava.

Biosci. Biotechnol. Biochem. 74 , 878-880, (2010)

Methanolic extracts of edible plants and seaweeds were tested for their inhibitory activity against Jack bean urease. Quercetin-4'-O-beta-D-glucopyranoside was isolated from Allium cepa as a urease in...

[Determination of avicularin in Polygonum aviculare L].

Yao Xue Xue Bao 18(9) , 700-4, (1983)

Synonyms

4H-1-Benzopyran-4-one, 3-(α-L-arabinofuranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

Fenicularin

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl α-L-arabinofuranoside

Quercetin 3-α-L-arabinofuranoside

Avicularin

QUERCETIN-3-ARABINOSIDE

Avicularoside

Avicularine

Avicularin,Quercetin 3-alpha-L-arabinofuranoside

Recommended......