CAS 5682-25-7|9-ALPHA-RIBOFURANOSYLADENINE

Introduction:Basic information about CAS 5682-25-7|9-ALPHA-RIBOFURANOSYLADENINE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name9-ALPHA-RIBOFURANOSYLADENINE
CAS Number5682-25-7Molecular Weight267.24
Density/Boiling Point/
Molecular FormulaC10H13N5O4Melting Point205-207 °C
MSDSChineseUSAFlash Point/
Symbol
GHS06
Signal WordDanger

Names

Namealpha-D-Adenosine
SynonymMore Synonyms

9-ALPHA-RIBOFURANOSYLADENINE BiologicalActivity

DescriptionAlpha-Adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Melting Point205-207 °C
Molecular FormulaC10H13N5O4
Molecular Weight267.24
Exact Mass267.09700
PSA139.54000
InChIKeyOIRDTQYFTABQOQ-CRKDRTNXSA-N
SMILESNc1ncnc2c1ncn2C1OC(CO)C(O)C1O
Storage condition-20°C

Safety Information

Symbol
GHS06
Signal WordDanger
Hazard StatementsH301
Precautionary StatementsP301 + P310
Hazard CodesT+
RIDADRUN 2811 6.1 / PGIII

Synonyms

α-D-adenosine
A-ADENOSINE
(1S)-1-(6-Amino-purin-9-yl)-D-1,4-anhydro-ribit
α-Adenosine
1-(6-amino-purin-9-yl)-α-L-1-deoxy-ribofuranose
ALPHA-ADENOSINE
α-adenosine
9-ALPHA-RIBOFURANOSYLADENINE
9H-PURIN-6-AMINE, 9-A-D-RIBOFURANOSYL-
1-α-D-ribofuranosyladenine
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