CAS 10101-89-0|Trisodium phosphate dodecahydrate
Introduction：Basic information about CAS 10101-89-0|Trisodium phosphate dodecahydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Trisodium phosphate dodecahydrate | ||
|---|---|---|---|
| CAS Number | 10101-89-0 | Molecular Weight | 380.18 |
| Density | 1.62 | Boiling Point | 158ºC at 760 mmHg |
| Molecular Formula | H24Na36O16P | Melting Point | 75 °C |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Trisodium phosphate dodecahydrate |
|---|---|
| Synonym | More Synonyms |
Trisodium phosphate dodecahydrate BiologicalActivity
| Description | Trisodium phosphate dodecahydrate is a corrosion inhibitor for iron in 0.1 M NaClO4, in both aerated and deaerated solutions. Trisodium phosphate dodecahydrate can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Armstrong R D, et al. Behaviour of sodium silicate and sodium phosphate (tribasic) as corrosion inhibitors for iron[J]. Journal of applied electrochemistry, 1994, 24: 1244-1248. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99. |
Chemical & Physical Properties
| Density | 1.62 |
|---|---|
| Boiling Point | 158ºC at 760 mmHg |
| Melting Point | 75 °C |
| Molecular Formula | H24Na36O16P |
| Molecular Weight | 380.18 |
| Exact Mass | 380.049500 |
| PSA | 206.82000 |
| Index of Refraction | 1.4458 |
| InChIKey | ASTWEMOBIXQPPV-UHFFFAOYSA-K |
| SMILES | O.O.O.O.O.O.O.O.O.O.O.O.O=P([O-])([O-])[O-].[Na+].[Na+].[Na+] |
| Storage condition | Store at RT. |
| Stability | Stable. Incompatible with strong acids. Keep dry. |
| Water Solubility | 258 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 430 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 257,791,1963 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1585 No. of Facilities: 154 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 308 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1585 No. of Facilities: 3662 (estimated) No. of Industries: 36 No. of Occupations: 31 No. of Employees: 31308 (estimated) No. of Female Employees: 6999 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C:Corrosive |
| Risk Phrases | R35 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 3262 8/PG 3 |
| WGK Germany | 1 |
| RTECS | TC9575000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2835291000 |
Customs
| HS Code | 2835291000 |
|---|
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Synonyms
| trisodium,phosphate,dodecahydrate |
| Sodium phosphate,tribasic dodecahydrate |
| MFCD00149198 |
| Sodium phosphate hydrate (3:1:12) |
| Phosphoric acid, trisodium salt, dodecahydrate |
| Trisodium phosphate dodecahydrate |
| Sodium phosphate tribasic dodecahydrate |
| EINECS 231-509-8 |
| Phosphoric acid trisodium salt dodecahydrate |
| Sodium phosphate dodecahydrate |
