CAS 220094-15-5|Boc-Ala-Glu-Val-Asp-aldehyde (pseudo acid)

Introduction:Basic information about CAS 220094-15-5|Boc-Ala-Glu-Val-Asp-aldehyde (pseudo acid), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBoc-Ala-Glu-Val-Asp-aldehyde (pseudo acid)
CAS Number220094-15-5Molecular Weight516.54
Density1.258Boiling Point/
Molecular FormulaC22H36N4O10Melting Point/
MSDS/Flash Point/

Names

NameBoc-Ala-Glu-Val-Asp-aldehyde (pseudo acid)
SynonymMore Synonyms

BiologicalActivity

DescriptionBoc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases[1][2].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisSignaling Pathways >>Apoptosis >>CaspaseResearch Areas >>Inflammation/Immunology
Target

Caspase 8[2].

References

[1]. Garcia-Calvo M, et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13.  

[2]. Grassmé H, et al. Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene. 2003 Aug 21;22(35):5457-70.  

Chemical & Physical Properties

Density1.258
Molecular FormulaC22H36N4O10
Molecular Weight516.54
Exact Mass516.24300
PSA217.30000
LogP1.11200
InChIKeyMAMIJEIFDIXCPX-WSMBLCCSSA-N
SMILESCC(NC(=O)OC(C)(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC(C=O)CC(=O)O)C(C)C

Synonyms

boc-ala-glu-val-asp-aldehyde
boc-aevd-cho
boc-ala-glu-val-asp-cho
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