CAS 153982-38-8|Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp)

Introduction:Basic information about CAS 153982-38-8|Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCyclo(-D-Ser-Pro-D-Val-Leu-D-Trp)
CAS Number153982-38-8Molecular Weight582.69100
Density/Boiling Point/
Molecular FormulaC30H42N6O6Melting Point/
MSDSChineseUSAFlash Point/

Names

Name(3R,6R,9S,12R,15S)-3-(hydroxymethyl)-6-(1H-indol-3-ylmethyl)-9-(2-methylpropyl)-12-propan-2-yl-1,4,7,10,13-pentazabicyclo[13.3.0]octadecane-2,5,8,11,14-pentone
SynonymMore Synonyms

Chemical & Physical Properties

Molecular FormulaC30H42N6O6
Molecular Weight582.69100
Exact Mass582.31700
PSA172.73000
LogP1.60170
InChIKeyFLVWONZBLRGQPK-UHFFFAOYSA-N
SMILESCC(C)CC1NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(CO)NC(=O)C(Cc2c[nH]c3ccccc23)NC1=O

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
WGK Germany3

Articles3

More Articles
Cardiac myocytes control release of endothelin-1 in coronary vasculature.

Am. J. Physiol. Heart Circ. Physiol. 288 , H2088-2092, (2005)

Alpha-adrenergic vasoconstriction in the coronary circulation is mediated through alpha-adrenoceptors on cardiac myocytes and subsequent release of endothelin, a very potent, long-lasting vasoconstric...

The hemodynamic effects of endothelin receptor antagonism during a venous air infusion in dogs.

Anesth. Analg. 90 , 102-106, (2000)

Endothelin (ET) is involved in the humoral component of the vasoconstriction during pulmonary embolism. We examined the effects of selective ET receptor antagonists on the hemodynamic and respiratory ...

Location of alkali metal binding sites in endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) and cyclo(D-Trp-D-Asp-Pro-D-Ile-Leu), from multistep collisionally activated decompositions.

J. Mass Spectrom. 35 , 265-276, (2000)

We previously showed by using mass spectrometry that endothelin A selective receptor antagonists BQ123 and JKC301 form novel coordination compounds with sodium ions. This property may underlie the abi...

Synonyms

cyclo(D-Ser-Pro-D-Val-Leu-D-Trp)
JKC 302
Cyclo(-D-Ser-Pro-D-Val-Leu-D-Trp)
CAS 136553-96-3|JKC-301
CAS 16691-00-2|Cyclo(-Glu-Glu)
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