CAS 2491-06-7|N,N-Dimethylglycine hydrochloride

Introduction:Basic information about CAS 2491-06-7|N,N-Dimethylglycine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN,N-Dimethylglycine hydrochloride
CAS Number2491-06-7Molecular Weight139.581
Density1.069g/cm3Boiling Point175.2ºC at 760 mmHg
Molecular FormulaC4H10ClNO2Melting Point189-194 °C(lit.)
MSDSChineseUSAFlash Point59.8ºC

Names

Name2-(dimethylamino)acetic acid,hydrochloride
SynonymMore Synonyms

N,N-Dimethylglycine hydrochloride BiologicalActivity

DescriptionN,N-Dimethylglycine hydrochloride is a Glycine (HY-Y0966) derivative[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroAmino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

Density1.069g/cm3
Boiling Point175.2ºC at 760 mmHg
Melting Point189-194 °C(lit.)
Molecular FormulaC4H10ClNO2
Molecular Weight139.581
Flash Point59.8ºC
Exact Mass139.040009
PSA40.54000
LogP0.43460
Vapour Pressure0.556mmHg at 25°C
InChIKeyFKASAVXZZLJTNX-UHFFFAOYSA-N
SMILESCN(C)CC(=O)O.Cl
Water Solubility100 g/L (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MB9995000
CHEMICAL NAME :
Glycine, N,N-dimethyl-, hydrochloride
CAS REGISTRY NUMBER :
2491-06-7
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C4-H9-N-O2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3900 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea
REFERENCE :
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,198,1992

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXi
Risk PhrasesR36/37/38
Safety PhrasesS22-S24/25
RIDADRNONH for all modes of transport
WGK Germany2
RTECSMB9995000
HS Code2922499990

Customs

HS Code2922499990
SummaryHS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles29

More Articles
Exposure to the proton scavenger glycine under alkaline conditions induces Escherichia coli viability loss.

PLoS ONE 8(3) , e60328, (2013)

Our previous work described a clear loss of Escherichia coli (E. coli) membrane integrity after incubation with glycine or its N-methylated derivatives N-methylglycine (sarcosine) and N,N-dimethylglyc...

DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.

Am. J. Clin. Nutr. 97(6) , 1217-27, (2013)

Animal models show that periconceptional supplementation with folic acid, vitamin B-12, choline, and betaine can induce differences in offspring phenotype mediated by epigenetic changes in DNA. In hum...

Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.

Am. J. Clin. Nutr. 97(6) , 1252-9, (2013)

Folate, choline, and betaine participate in homocysteine metabolism. It is not known whether they interact during pregnancy.The objective was to investigate how folate status affects choline, betaine,...

Synonyms

Glycine, N,N-dimethyl-, hydrochloride (1:1)
N,N-Dimethyl glycine hydrochloride
Me2NCH2CO2H hydrochloride
glycine-N',N'-dimethylamide hydrochloride
n,n-dimethylglycine hydrochloride(1:1)
Glycine,N,N-dimethyl-,hydrochloride
Me2NCH2CO2H*HCl
MFCD00012610
N,N-Dimethylglycine hydrochloride
N,N-Dimethylglycine hydrochloride (1:1)
N-Methylsarcosine hydrochloride
N,N-Dimethylglycine Hcl
(Dimethylamino)acetic acid hydrochloride
N,N-dimethylglycine*HCl
N,N-dimethyl-glycine hydrochloride
N,N-Dimethylaminoacetic acid hydrochloride
N,N-Dimethylglycinium chloride
EINECS 219-648-2
Dimethylglycine hydrochloride
CAS 2941-20-0|1-phenylpropylamine
CAS 30652-11-0|Deferiprone
Recommended......
TOP