CAS 4320-30-3|L-Arginine L-glutamate
| Common Name | L-Arginine L-glutamate | ||
|---|---|---|---|
| CAS Number | 4320-30-3 | Molecular Weight | 321.330 |
| Density | / | Boiling Point | 409.1ºC at 760 mmHg |
| Molecular Formula | C11H23N5O6 | Melting Point | 191 - 192ºC |
| MSDS | USA | Flash Point | 201.2ºC |
Names
| Name | (S)-2-Amino-5-guanidinopentanoic acid compound with (S)-2-aminopentanedioic acid (1:1) |
|---|---|
| Synonym | More Synonyms |
L-Arginine L-glutamate BiologicalActivity
| Description | L-Arginine L-glutamate ((S)-(+)-Arginine L-glutamate) is the nitrogen donor for synthesis of nitric oxide. L-Arginine L-glutamate can be used for upper gastrointestinal hypofunction or dysfunction like functional dyspepsia research[1]. |
|---|---|
| Related Catalog | Research Areas >>Metabolic Disease |
| Target | Microbial Metabolite Human Endogenous Metabolite |
| In Vivo | L-Arginine L-glutamate (10-30 mg/kg, p.o.) dose-dependently promotes gastric emptying in rats. This effect is dependent on vagus nerve activation. Intragastric L-Arginine L-glutamate (3-30 mg/kg intragastrically) also dose-dependently enhances adaptive relaxation of rat stomachs. |
| References | [1]. Ikumi Ishibashi-Shiraishi, et al. L-Arginine L-Glutamate Enhances Gastric Motor Function in Rats and Dogs and Improves Delayed Gastric Emptying in Dogs. J Pharmacol Exp Ther. 2016 Nov;359(2):238-246. |
Chemical & Physical Properties
| Boiling Point | 409.1ºC at 760 mmHg |
|---|---|
| Melting Point | 191 - 192ºC |
| Molecular Formula | C11H23N5O6 |
| Molecular Weight | 321.330 |
| Flash Point | 201.2ºC |
| Exact Mass | 321.164825 |
| PSA | 225.84000 |
| LogP | 0.51620 |
| InChIKey | RVEWUBJVAHOGKA-WOYAITHZSA-N |
| SMILES | NC(CCC(=O)O)C(=O)O.NC(N)=NCCCC(N)C(=O)O |
| Storage condition | −20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
Articles18
More Articles| Arginine glutamate improves healing of radiation-induced skin ulcers in guinea pigs. Int. J. Radiat. Biol. 89(12) , 1108-15, (2013) The increase in the incidence of the radiation-induced skin injury cases and the absence of standard treatments escalate the interest in finding new and effective drugs for these lesions. We studied t... | |
| Effect of biotin on ammonia intoxication in rats and mice. J. Gastroenterol. 30(3) , 351-5, (1995) The effects of biotin on ammonia concentration in blood and brain were evaluated in hyperammonemic rats and mice. Rats were injected with 5 mmol/kg BW of ammonium acetate, and mice were injected with ... | |
| Circular dichroism and ultraviolet resonance Raman indicate little Arg-Glu side chain α-helix peptide stabilization. J. Phys. Chem. B 115(14) , 4234-43, (2011) Electrostatic interactions between side chains can control the conformation and folding of peptides and proteins. We used circular dichroism (CD) and ultraviolet (UV) resonance Raman spectroscopy (UVR... |
Synonyms
| Arginine glutamate |
| EINECS 224-350-0 |
| Glutargin |
| Argimate |
| L-Glutamic acid, compd. with L-arginine (1:1) |
| L-Arginine - L-glutamic acid (1:1) |
| L-Arginine glutamate |
| S(+)-2-Amino-5-guanidinopentanoic acid L-glutamate salt |
| Glutepar |
| L-Arginine L-glutamate |
| L-Glutamic Acid compd. with L-Arginine (1:1) |
| MFCD06408000 |
| L-Arginine, compd. with L-glutamic acid (1:1) |
| Ginamate |
