CAS 2213-63-0|2,3-Dichloroquinoxaline

Introduction：Basic information about CAS 2213-63-0|2,3-Dichloroquinoxaline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles5
6. Synonyms

Common Name	2,3-Dichloroquinoxaline
CAS Number	2213-63-0	Molecular Weight	199.037
Density	1.5±0.1 g/cm3	Boiling Point	269.7±35.0 °C at 760 mmHg
Molecular Formula	C₈H₄Cl₂N₂	Melting Point	152-154 °C(lit.)
MSDS	ChineseUSA	Flash Point	142.9±11.5 °C
Symbol	GHS06	Signal Word	Danger

Names

Name	2,3-Dichloroquinoxaline
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	269.7±35.0 °C at 760 mmHg
Melting Point	152-154 °C(lit.)
Molecular Formula	C₈H₄Cl₂N₂
Molecular Weight	199.037
Flash Point	142.9±11.5 °C
Exact Mass	197.975159
PSA	25.78000
LogP	3.04
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.671
InChIKey	SPSSDDOTEZKOOV-UHFFFAOYSA-N
SMILES	Clc1nc2ccccc2nc1Cl
Stability	Stable. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VD1720000

CHEMICAL NAME :: Quinoxaline, 2,3-dichloro-

CAS REGISTRY NUMBER :: 2213-63-0

BEILSTEIN REFERENCE NO. :: 0126076

LAST UPDATED :: 199806

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H4-Cl2-N2

MOLECULAR WEIGHT :: 199.04

WISWESSER LINE NOTATION :: T66 BN ENJ CG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 195 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Gastrointestinal - peritonitis Kidney, Ureter, Bladder - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534573

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5600 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03256

Safety Information

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H315-H319-H335
Precautionary Statements	P261-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25;R36/37/38
Safety Phrases	S26-S36/37/39-S45-S37/39-S28A
RIDADR	2811
WGK Germany	3
RTECS	VD1720000
Packaging Group	III
Hazard Class	6.1

Articles5

Synthesis of some new pyrimido[2',1':2,3]thiazolo[4,5-b]quinoxaline derivatives as anti-inflammatory and analgesic agents.

Eur. J. Med. Chem. 45 , 1976-81, (2010)

Treatment of 6-aminothiouracil (1) with 2,3-dichloroquinoxaline (2) in ethanol/TEA afforded 6-amino-2-(3-chloroquinoxalin-2-ylthio)pyrimidin-4(3H)-one (3), which was refluxed in DMF to give 2-aminopyr...

Synthesis, structure elucidation and antibacterial evaluation of new steroidal -5-en-7-thiazoloquinoxaline derivatives.

Eur. J. Med. Chem. 43 , 2257-61, (2008)

Some heterocyclic systems namely cholest-5-en-7-thiazolo[4,5-b]quinoxaline-2-yl-hydrazone] were synthesized by the reaction of cholest-5-en-7-one-thiosemicarbazone with 2,3-dichloroquinoxaline at 80 d...

AlCl3 induced (hetero)arylation of 2,3-dichloroquinoxaline: a one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents.

Bioorg. Med. Chem. 20(5) , 1711-22, (2012)

A direct and single-step method has been developed for the synthesis of mono and 2,3-disubstituted quinoxalines by using a AlCl(3) induced (hetero)arylation of 2,3-dichloroquinoxaline. Both symmetrica...

Synonyms

2,3-Dichloroquinoxaline

2,3-DICHLORO-QUINOXALINE

2,3,6-TRIFLUOROBENZOICACID

2,3-dichloroquinoxazoline

2,3-dichloroquinaxoline

Quinoxaline,2,3-dichloro

Quinoxaline, 2,3-dichloro-

EINECS 218-667-3

MFCD00006720

2,3-dichloro quinoxaline

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