CAS 524-40-3|RICININE

Introduction:Basic information about CAS 524-40-3|RICININE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameRICININE
CAS Number524-40-3Molecular Weight164.16
Density1.23 g/cm3Boiling Point370.9ºC at 760 mmHg
Molecular FormulaC8H8N2O2Melting Point200-201ºC
MSDSChineseUSAFlash Point178.1ºC
Symbol
GHS02, GHS07
Signal WordDanger

Names

Namericinine
SynonymMore Synonyms

RICININE BiologicalActivity

DescriptionRicinine exhibits hepatoprotection in CCl4 -induced liver damage[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Oriakhi K, et al. Isolation, characterization, and hepatoprotective properties of betulinic acid and ricinine from Tetracarpidium conophorum seeds (Euphorbiaceae). J Food Biochem. 2021;45(3):e13288. 

Chemical & Physical Properties

Density1.23 g/cm3
Boiling Point370.9ºC at 760 mmHg
Melting Point200-201ºC
Molecular FormulaC8H8N2O2
Molecular Weight164.16
Flash Point178.1ºC
Exact Mass164.05900
PSA55.02000
LogP0.26558
Index of Refraction1.547
InChIKeyPETSAYFQSGAEQY-UHFFFAOYSA-N
SMILESCOc1ccn(C)c(=O)c1C#N

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QT3100000
CHEMICAL NAME :
Nicotinonitrile, 1,2-dihydro-4-methoxy-1-methyl-2-oxo-
CAS REGISTRY NUMBER :
524-40-3
BEILSTEIN REFERENCE NO. :
0139222
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H8-N2-O2
MOLECULAR WEIGHT :
164.18
WISWESSER LINE NOTATION :
T6NVJ A1 CCN DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,23,1953

Safety Information

Symbol
GHS02, GHS07
Signal WordDanger
Hazard StatementsH225-H302 + H312 + H332-H319
Precautionary StatementsP210-P261-P302 + P352 + P312-P304 + P340 + P312-P337 + P313-P403 + P235
Hazard CodesT,Xn,F
Risk Phrases25-36-20/21/22-11
Safety Phrases45-36/37-16
RIDADRUN 2811 6.1 / PGIII
RTECSQT3100000
HS Code2933399090

Customs

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles15

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Plant poisonings have left their mark on history and still cause many deaths, whether intentional or accidental. The means to show toxicological evidence of such poisonings should be implemented with ...

Neutralising antibodies against ricin toxin.

PLoS ONE 6 , e20166, (2011)

The Centers for Disease Control and Prevention have listed the potential bioweapon ricin as a Category B Agent. Ricin is a so-called A/B toxin produced by plants and is one of the deadliest molecules ...

Activity of Ricinus communis (Euphorbiaceae) and ricinine against the leaf-cutting ant Atta sexdens rubropilosa (Hymenoptera: Formicidae) and the symbiotic fungus Leucoagaricus gongylophorus.

Pest Manag. Sci. 60(9) , 933-8, (2004)

The focus of this study was the identification of compounds from plant extracts for use in crop protection. This paper reports on the toxic activity of fractions of leaf extracts of Ricinus communis L...

Synonyms

Recinine
4-methoxy-1-methyl-2-oxopyridine-3-carbonitrile
Ritsinin
4-Methoxy-1-methyl-2-oxo-1,2-dihydro-pyridin-3-carbonitril
4-methoxy-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile
RICININE
Ricidine
Ricinin
Recinine Ricidine Ricinin Ritsinin
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