Introduction：Basic information about CAS 737-52-0|Oxypeucedanin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Oxypeucedanin |
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| CAS Number | 737-52-0 | Molecular Weight | 286.279 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 469.6±45.0 °C at 760 mmHg |
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| Molecular Formula | C16H14O5 | Melting Point | 141-142 °C |
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| MSDS | / | Flash Point | 237.8±28.7 °C |
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Names
| Name | oxypeucedanin |
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| Synonym | More Synonyms |
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Oxypeucedanin BiologicalActivity
| Description | Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation[1]. Oxypeucedanin induces cell apoptosis through inhibition of cancer cell migration[2]. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>Potassium Channel |
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| Target | IC50: HKv1.5 current; apoptosis[1] |
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| References | [1]. Eun JS, et al. Effects of oxypeucedanin on hKv1.5 and action potential duration.Biol Pharm Bull. 2005 Apr;28(4):657-60. [2]. Yu Liu, et al. Oxypeucedanin hydrate monoacetate isolated from Angelica dahurica induces apoptosis in Caco-2 colon carcinoma cells through the mediation of PI3K-signalling pathway and inhibition of cancer cell migration |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 469.6±45.0 °C at 760 mmHg |
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| Melting Point | 141-142 °C |
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| Molecular Formula | C16H14O5 |
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| Molecular Weight | 286.279 |
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| Flash Point | 237.8±28.7 °C |
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| Exact Mass | 286.084137 |
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| PSA | 65.11000 |
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| LogP | 2.17 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.634 |
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| InChIKey | QTAGQHZOLRFCBU-UHFFFAOYSA-N |
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| SMILES | CC1(C)OC1COc1c2ccoc2cc2oc(=O)ccc12 |
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| Storage condition | 2-8°C |
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Safety Information
Synonyms
| 4-(3,3-Dimethyl-oxiranylmethoxy)-furo[3,2-g]chromen-7-one |
| 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((3,3-dimethyloxiranyl)methoxy)- |
| 5-[(3,3-Dimethyl-2-oxiranyl)methoxy]-7H-furo[3,2-g]chromen-7-one |
| 4-[(3,3-Dimethyl-2-oxiranyl)methoxy]-7H-furo[3,2-g]chromen-7-one |
| 7H-Furo[3,2-g][1]benzopyran-7-one, 5-[(3,3-dimethyloxiranyl)methoxy]- |
| 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[(3,3-dimethyloxiranyl)methoxy]- |
| Oxypencedanin |
| 5-[(3,3-Dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g]chromen-7-one |
| oxypeucadanin |
