CAS 623-48-3|Ethyl iodoacetate

Introduction：Basic information about CAS 623-48-3|Ethyl iodoacetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	Ethyl iodoacetate
CAS Number	623-48-3	Molecular Weight	214.00200
Density	1.808 g/mL at 25 °C(lit.)	Boiling Point	179-180 °C(lit.)
Molecular Formula	C₄H₇IO₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	170 °F
Symbol	GHS05, GHS06	Signal Word	Danger

Names

Name	ethyl 2-iodoacetate
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.808 g/mL at 25 °C(lit.)
Boiling Point	179-180 °C(lit.)
Molecular Formula	C₄H₇IO₂
Molecular Weight	214.00200
Flash Point	170 °F
Exact Mass	213.94900
PSA	26.30000
LogP	0.98450
Index of Refraction	n20/D 1.503(lit.)
InChIKey	MFFXVVHUKRKXCI-UHFFFAOYSA-N
SMILES	CCOC(=O)CI
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AI3575000

CHEMICAL NAME :: Acetic acid, iodo-, ethyl ester

CAS REGISTRY NUMBER :: 623-48-3

BEILSTEIN REFERENCE NO. :: 0741934

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C4-H7-I-O2

MOLECULAR WEIGHT :: 214.01

WISWESSER LINE NOTATION :: I1VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: 0TS0570989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: 0TS0570989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: 0TS0570989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Lungs, Thorax, or Respiration - other changes Nutritional and Gross Metabolic - other changes

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 31,297,1963

Safety Information

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H300-H314
Precautionary Statements	P264-P280-P301 + P310-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T: Toxic;
Risk Phrases	R25;R34
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 2922 8/PG 2
WGK Germany	3
RTECS	AI3575000
Packaging Group	II
Hazard Class	6.1
HS Code	2915900090

Customs

HS Code	2915900090
Summary	2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles1

Synthesis of a leucomitosane via a diastereoselective radical cascade.

J. Org. Chem. 78(12) , 6245-52, (2013)

The preparation of trans-2,3-disubstituted indolines from 1-azido-2-allylbenzene derivatives via a diastereoselective radical cascade using ethyl iodoacetate and triethylborane is described. Further l...

Synonyms

ETHYL IODOACETATE

Ethyl monoiodoacetate

MFCD00001081

Acetic acid,iodo-,ethyl ester

Iodoacetic acid,ethyl ester

EINECS 210-796-3

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