CAS 88337-96-6|15-Acetyl-deoxynivalenol

Introduction：Basic information about CAS 88337-96-6|15-Acetyl-deoxynivalenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 15-Acetyl-deoxynivalenol BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Articles45
7. Synonyms

Common Name	15-Acetyl-deoxynivalenol
CAS Number	88337-96-6	Molecular Weight	338.35200
Density	1.42g/cm3	Boiling Point	518.8ºC at 760 mmHg
Molecular Formula	C₁₇H₂₂O₇	Melting Point	185°C-187°C
MSDS	ChineseUSA	Flash Point	2ºC
Symbol	GHS06	Signal Word	Danger

Names

Name	15-acetoxy-3alpha,7alpha-dihydroxy-12,13-epoxytrichothec-9-en-8-one
Synonym	More Synonyms

15-Acetyl-deoxynivalenol BiologicalActivity

Description	15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells[1].
Related Catalog	Research Areas >>Cancer
References	[1]. Juan-García A, et al. Binary and tertiary combination of alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on HepG2 cells: Toxic effects and evaluation of degradation products. Toxicol In Vitro. 2016 Aug;34:264-273.

Chemical & Physical Properties

Density	1.42g/cm3
Boiling Point	518.8ºC at 760 mmHg
Melting Point	185°C-187°C
Molecular Formula	C₁₇H₂₂O₇
Molecular Weight	338.35200
Flash Point	2ºC
Exact Mass	338.13700
PSA	105.59000
Index of Refraction	1.595
InChIKey	IDGRYIRJIFKTAN-HTJQZXIKSA-N
SMILES	CC(=O)OCC12C(C=C(C)C(=O)C1O)OC1C(O)CC2(C)C12CO2
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YD0155000

CHEMICAL NAME :: Trichothec-9-en-8-one, 15-(acetyloxy)-12,13-epoxy-3,7-dihydroxy-, (3-alpha,7-alpha)-

CAS REGISTRY NUMBER :: 88337-96-6

LAST UPDATED :: 198708

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H22-O7

MOLECULAR WEIGHT :: 338.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 34 mg/kg

TOXIC EFFECTS :: Gastrointestinal - ulceration or bleeding from small intestine Kidney, Ureter, Bladder - inflammation, necrosis, or scarring of bladder Blood - changes in spleen

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 25,155,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 113 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 50,1304,1985

Safety Information

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300-H311-H331
Precautionary Statements	P261-P264-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T,Xn,F
Risk Phrases	23/24/25-36-20/21/22-11
Safety Phrases	36/37-45-26
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
RTECS	YD0155000
Packaging Group	I
Hazard Class	6.1(a)
HS Code	29329990

Articles45

Development and validation of a high performance liquid chromatographic-mass spectrometry method for the simultaneous quantification of 10 trichothecenes in ultra-high temperature processed cow milk.

J. Chromatogr. A. 1419 , 37-44, (2015)

An LC-MS/MS (QqQ) method has been developed and validated for simultaneous determination of the following trichothecenes in UHT cow milk: nivalenol (NIV), deoxynivalenol (DON), deepoxy-deoxynivalenol ...

Innate Immune Sensing of Fusarium culmorum by Mouse Dendritic Cells.

J. Toxicol. Environ. Health A 78 , 871-85, (2015)

Chronic inhalation of grain dust is associated with asthma and chronic bronchitis in grain worker populations. Exposure to fungal particles was postulated to be an important etiologic agent of these p...

Determination of the Mycotoxin Content in Distiller's Dried Grain with Solubles Using a Multianalyte UHPLC-MS/MS Method.

J. Agric. Food Chem. 63 , 9441-51, (2015)

There are more than 300 potential mycotoxins that can contaminate food and feed and cause adverse effects in humans and animals. The data on the co-occurrence of mycotoxins in novel animal feed materi...

Synonyms

15-ADON

15-ACETYLDEOXYNIVALENOL

Deoxynivalenol 15-Acetate

15-acetoxy-3,7-dihydroxy-12,13-epoxytrichothec-9-en-8-one

15-O-acetyl-4-deoxynivalenol

15-ACETYLVOMITOXIN

15-acetyl

15-Acetyl-4-deoxynivalenol

3-ACETYL-D3-DEOXYNIVALENOL

15-ACDON

DON-15-acetate

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