CAS 622-40-2|2-Morpholinoethanol

Introduction：Basic information about CAS 622-40-2|2-Morpholinoethanol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	2-Morpholinoethanol
CAS Number	622-40-2	Molecular Weight	131.173
Density	1.1±0.1 g/cm3	Boiling Point	224.4±20.0 °C at 760 mmHg
Molecular Formula	C₆H₁₃NO₂	Melting Point	-1 °C
MSDS	ChineseUSA	Flash Point	99.4±0.0 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	2-(morpholin-4-yl)ethanol
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	224.4±20.0 °C at 760 mmHg
Melting Point	-1 °C
Molecular Formula	C₆H₁₃NO₂
Molecular Weight	131.173
Flash Point	99.4±0.0 °C
Exact Mass	131.094635
PSA	32.70000
LogP	-0.60
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.470
InChIKey	KKFDCBRMNNSAAW-UHFFFAOYSA-N
SMILES	OCCN1CCOCC1
Storage condition	2-8°C
Water Solubility	miscible

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QE3510000

CHEMICAL NAME :: 4-Morpholineethanol

CAS REGISTRY NUMBER :: 622-40-2

BEILSTEIN REFERENCE NO. :: 0104375

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C6-H13-N-O2

MOLECULAR WEIGHT :: 131.20

WISWESSER LINE NOTATION :: T6N DOTJ A2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5500 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >16 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 1 gm/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 136,153,1984

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	QE3510000
HS Code	29349990

Customs

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles2

Impact of the structure of biocompatible aliphatic polycarbonates on siRNA transfection ability.

Biomacromolecules 16(3) , 769-79, (2015)

RNAi therapeutics are promising therapeutic tools that have sparked the interest of many researchers. In an effort to provide a safe alternative to PEI, we have designed a series of new guanidinium- a...

Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes.

Bioorg. Med. Chem. 19 , 5679-92, (2011)

In this work libraries of morpholines and oxazepanes have been prepared via the reductive amination reaction between dialdehydes, derived from carbohydrates, and a range of amines. In this way, functi...

Synonyms

2-(4-Morpholinyl)ethanol

4-Morpholineethanol

2-Morpholinoethanol

β-Morpholinoethanol

MFCD00006180

EINECS 210-734-5

4-(2-hydroxyethyl)morpholine

2-morpholin-4-ylethanol

2-(morpholin-4-yl)ethanol

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