CAS 104774-87-0|Cinacalcet metabolite M4

Introduction：Basic information about CAS 104774-87-0|Cinacalcet metabolite M4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Cinacalcet metabolite M4 BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Cinacalcet metabolite M4
CAS Number	104774-87-0	Molecular Weight	203.204
Density	1.2±0.1 g/cm3	Boiling Point	222.2±40.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₂F₃N	Melting Point	/
MSDS	/	Flash Point	92.6±12.0 °C

Names

Name	3-[3-(trifluoromethyl)phenyl]propan-1-amine
Synonym	More Synonyms

Cinacalcet metabolite M4 BiologicalActivity

Description	Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].
Related Catalog	Research Areas >>Cardiovascular Disease
References	[1]. Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500. [2]. Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.

Description

Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2].

Related Catalog

Research Areas >>Cardiovascular Disease

References

[1]. Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500.

[2]. Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	222.2±40.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₂F₃N
Molecular Weight	203.204
Flash Point	92.6±12.0 °C
Exact Mass	203.092178
PSA	26.02000
LogP	2.40
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.468
InChIKey	JMTLMFBJIQWJPW-UHFFFAOYSA-N
SMILES	NCCCc1cccc(C(F)(F)F)c1

Safety Information

Hazard Codes	Xi
HS Code	2921499090

Customs

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synonyms

3-[3-(Trifluoromethyl)phenyl]-1-propanamine

Benzenepropanamine, 3-(trifluoromethyl)-

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