Introduction：Basic information about CAS 107622-80-0|4-Phenoxybenzylamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Phenoxybenzylamine |
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| CAS Number | 107622-80-0 | Molecular Weight | 199.248 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 319.6±25.0 °C at 760 mmHg |
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| Molecular Formula | C13H13NO | Melting Point | / |
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| MSDS | USA | Flash Point | 149.5±16.4 °C |
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Names
| Name | 4-Phenoxybenzylamine |
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| Synonym | More Synonyms |
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4-Phenoxybenzylamine BiologicalActivity
| Description | 4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against FL NS3/4a. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>HCVResearch Areas >>Infection |
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| Target | IC50: 500 μM (FL NS3/4a)[1] |
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| In Vitro | A highly conserved novel binding site located at the interface between the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein is identified. 4-Phenoxybenzylamine binding at this allosteric site inhibits the function of the NS3 protein by stabilizing an inactive conformation and thus represents a new class of direct acting antiviral agents[1]. |
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| References | [1]. Saalau-Bethell SM, et al. Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function. Nat Chem Biol. 2012 Nov;8(11):920-5. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 319.6±25.0 °C at 760 mmHg |
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| Molecular Formula | C13H13NO |
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| Molecular Weight | 199.248 |
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| Flash Point | 149.5±16.4 °C |
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| Exact Mass | 199.099716 |
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| PSA | 35.25000 |
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| LogP | 3.08 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.595 |
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| InChIKey | CCAZAGUSBMVSAR-UHFFFAOYSA-N |
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| SMILES | NCc1ccc(Oc2ccccc2)cc1 |
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Safety Information
| Hazard Codes | C: Corrosive;Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | 26-36/37/39 |
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| HS Code | 2922299090 |
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Customs
| HS Code | 2922299090 |
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| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| (4-Phenoxyphenyl)methanamine |
| MFCD01310836 |
| Benzenemethanamine, 4-phenoxy- |
| 1-(4-Phenoxyphenyl)methanamine |
