Introduction：Basic information about CAS 882847-32-7|Fmoc-amino-PEG5-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-amino-PEG5-acid |
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| CAS Number | 882847-32-7 | Molecular Weight | 531.59500 |
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| Density | 1.210±0.06 g/cm3 (20ºC 760 Torr) | Boiling Point | 711.4±60.0°C at 760 mmHg |
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| Molecular Formula | C28H37NO9 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azadocosan-22-oic acid |
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| Synonym | More Synonyms |
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Fmoc-amino-PEG5-acid BiologicalActivity
| Description | Fmoc-amino-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.210±0.06 g/cm3 (20ºC 760 Torr) |
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| Boiling Point | 711.4±60.0°C at 760 mmHg |
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| Molecular Formula | C28H37NO9 |
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| Molecular Weight | 531.59500 |
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| Exact Mass | 531.24700 |
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| PSA | 121.78000 |
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| LogP | 3.47370 |
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| InChIKey | TWQTXZPTZPOEEB-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
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Safety Information
Synonyms
| fmoc-18-amino-4,7,10,13,16-pentaoxaoctadecanoic acid |
| 5,8,11,14,17-Pentaoxa-2-azaeicosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester |
